{"title":"Recovery","description":"\u003cp\u003eOur recovery peptide collection features compounds studied for tissue healing, inflammation modulation, and injury repair. Each peptide is research-grade with ≥98% HPLC-verified purity.\u003c\/p\u003e\n\n\u003ch3\u003ePrimary Recovery Peptides\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eBPC-157\u003c\/strong\u003e - Body protecting compound researched for tendon, ligament, and gut healing\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTB-500\u003c\/strong\u003e - Tissue repair peptide studied for wound healing and inflammation reduction\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGHK-Cu\u003c\/strong\u003e - Copper peptide investigated for skin repair and anti-inflammatory effects\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eKPV\u003c\/strong\u003e - Anti-inflammatory tripeptide researched for gut health and immune modulation\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLL-37\u003c\/strong\u003e - Antimicrobial peptide studied for wound healing and immune defense\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003eResearch Focus Areas\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eSoft tissue repair (tendons, ligaments, muscles)\u003c\/li\u003e\n\u003cli\u003eAngiogenesis and vascular health\u003c\/li\u003e\n\u003cli\u003eInflammation resolution and immune balance\u003c\/li\u003e\n\u003cli\u003eGut barrier function and mucosal healing\u003c\/li\u003e\n\u003cli\u003eWound healing and tissue remodeling\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003e\u003cstrong\u003eResearch Quality:\u003c\/strong\u003e Peptides BioLab recovery peptides are manufactured for research purposes only, tested to ≥98% purity (HPLC), and include batch-specific COA documentation. Not intended for human use.\u003c\/p\u003e","products":[{"product_id":"glutathione-1500mg","title":"Glutathione 1500MG","description":"\u003cdiv class=\"pb-product-desc\"\u003e\n\u003ch2\u003eGlutathione — Master Antioxidant Tripeptide for Redox Research\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eGlutathione\u003c\/strong\u003e (GSH) is the most abundant intracellular thiol antioxidant, present at millimolar concentrations in virtually all cells. The GSH\/GSSG ratio is a critical indicator of cellular redox status, with perturbations linked to numerous pathological conditions.\u003c\/p\u003e\n\u003ch3\u003eMechanism of Action\u003c\/h3\u003e\n\u003cp\u003eGlutathione scavenges ROS\/RNS directly, serves as cofactor for GPx and GST families, maintains protein thiol states, and recycles vitamins C and E. Depletion below 30% triggers mitochondrial dysfunction and apoptosis (\u003cem\u003eFree Radical Biology and Medicine\u003c\/em\u003e).\u003c\/p\u003e\n\u003ch3\u003eKey Research Areas\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eOxidative Stress Research:\u003c\/strong\u003e Benchmark antioxidant in redox biology — GSH supplementation and depletion protocols study how redox balance influences signaling and cell fate.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMitochondrial Function:\u003c\/strong\u003e Mitochondrial GSH pool protects electron transport chain and cardiolipin; depletion is an early apoptotic event.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDetoxification:\u003c\/strong\u003e GST enzymes conjugate glutathione to electrophilic substrates for phase II detoxification research.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eImmune Cell Function:\u003c\/strong\u003e Intracellular GSH levels regulate lymphocyte proliferation, NK cytotoxicity, and Th1\/Th2 balance.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eWhy Researchers Choose Peptides BioLab\u003c\/h3\u003e\n\u003cp\u003eEvery batch of \u003cstrong\u003eGlutathione\u003c\/strong\u003e supplied by Peptides BioLab undergoes rigorous HPLC and mass spectrometry analysis, ensuring ≥98% purity verified by an independent Certificate of Analysis (CoA). Our \u003ca href=\"\/products\/glutathione-1500mg\"\u003eGlutathione\u003c\/a\u003e is supplied as a lyophilized powder for maximum stability and shelf life, shipped worldwide from our state-of-the-art facilities in temperature-controlled packaging.\u003c\/p\u003e\n\u003ch3\u003eRelated Research Peptides\u003c\/h3\u003e\n\u003cp\u003eResearchers studying related pathways may also find these compounds relevant: \u003ca href=\"\/products\/nad\"\u003eNAD+\u003c\/a\u003e, \u003ca href=\"\/products\/ss-31\"\u003eSS-31\u003c\/a\u003e, and \u003ca href=\"\/products\/ghk-cu\"\u003eGHK-Cu\u003c\/a\u003e. Browse our \u003ca href=\"\/collections\/anti-aging\"\u003eAnti-Aging Research\u003c\/a\u003e collection.\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eFor research purposes only — Not for human consumption. All products are intended solely for in-vitro research and laboratory use.\u003c\/em\u003e\u003c\/p\u003e\n\u003c\/div\u003e","brand":"Peptides BioLab","offers":[{"title":"Default Title","offer_id":60995751379274,"sku":"PBL-GLUTATHIONE1500MG-10MG","price":44.99,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0998\/9429\/6906\/files\/peptides-biolab-glutathione-antioxidant-1500mg-research-grade.webp?v=1773933882"},{"product_id":"ara-290","title":"Ara-290","description":"\u003cdiv class=\"pb-product-desc\"\u003e\n\u003ch2\u003eARA-290 — Innate Repair Receptor Agonist for Neuroprotection Research\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eARA-290\u003c\/strong\u003e (Cibinetide) is an 11-amino acid peptide derived from erythropoietin (EPO) that selectively activates the innate repair receptor (IRR), a heterocomplex of EPO receptor and CD131. Unlike EPO, it does not stimulate erythropoiesis. Published in \u003cem\u003eMolecular Medicine\u003c\/em\u003e (2008) by Brines et al.\u003c\/p\u003e\n\u003ch3\u003eMechanism of Action\u003c\/h3\u003e\n\u003cp\u003eARA-290 binds the IRR heterocomplex, triggering JAK2\/STAT5 and PI3K\/Akt cascades that promote cell survival and modulate inflammatory cytokines. It suppresses NF-κB activation and reduces TNF-α, IL-6, IL-1β in macrophage models. In neural tissue, it protects against ischemia-reperfusion injury.\u003c\/p\u003e\n\u003ch3\u003eKey Research Areas\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eNeuroprotection:\u003c\/strong\u003e Promotes nerve fiber regeneration and restores sensory function in sciatic nerve injury models.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAnti-Inflammatory Signaling:\u003c\/strong\u003e Shifts macrophage polarization from M1 to M2 (reparative) phenotypes in chronic inflammation models.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMetabolic Neuropathy:\u003c\/strong\u003e Preserves intraepidermal nerve fiber density in diabetic neuropathy models.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTissue-Protective Signaling:\u003c\/strong\u003e Activates cytoprotective pathways independent of erythropoiesis for clean tissue repair research.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eWhy Researchers Choose Peptides BioLab\u003c\/h3\u003e\n\u003cp\u003eEvery batch of \u003cstrong\u003eARA-290\u003c\/strong\u003e supplied by Peptides BioLab undergoes rigorous HPLC and mass spectrometry analysis, ensuring ≥98% purity verified by an independent Certificate of Analysis (CoA). Our \u003ca href=\"\/products\/ara-290\"\u003eARA-290\u003c\/a\u003e is supplied as a lyophilized powder for maximum stability and shelf life, shipped worldwide from our state-of-the-art facilities in temperature-controlled packaging.\u003c\/p\u003e\n\u003ch3\u003eRelated Research Peptides\u003c\/h3\u003e\n\u003cp\u003eResearchers studying related pathways may also find these compounds relevant: \u003ca href=\"\/products\/vip\"\u003eVIP\u003c\/a\u003e, \u003ca href=\"\/products\/bpc-157\"\u003eBPC-157\u003c\/a\u003e, and \u003ca href=\"\/products\/kpv\"\u003eKPV\u003c\/a\u003e. Browse our \u003ca href=\"\/collections\/cognitive-function\"\u003eNeurological Research\u003c\/a\u003e collection.\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eFor research purposes only — Not for human consumption. All products are intended solely for in-vitro research and laboratory use.\u003c\/em\u003e\u003c\/p\u003e\n\u003c\/div\u003e","brand":"Peptides BioLab","offers":[{"title":"Default Title","offer_id":60995751706954,"sku":"PBL-ARA-290-6G","price":39.99,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0998\/9429\/6906\/files\/peptides-biolab-ara-290-peptide-10mg-research-grade.webp?v=1773933873"},{"product_id":"ll-37","title":"LL-37","description":"\u003cdiv class=\"pb-product-desc\"\u003e\n\u003ch2\u003eLL-37 — Human Cathelicidin Antimicrobial Peptide for Innate Immunity Research\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eLL-37\u003c\/strong\u003e is a 37-amino acid cationic antimicrobial peptide — the only human cathelicidin. Cleaved from hCAP18 by proteinase 3, it adopts an amphipathic alpha-helix for membrane disruption. Sequenced by Gudmundsson et al. (1996). Active against bacteria, fungi, and enveloped viruses.\u003c\/p\u003e\n\u003ch3\u003eMechanism of Action\u003c\/h3\u003e\n\u003cp\u003eLL-37 disrupts microbial membranes through electrostatic attraction to anionic phospholipids via carpet model, toroidal pore, and membrane thinning mechanisms. Also activates FPRL1, promotes chemotaxis, stimulates angiogenesis, and modulates TLR signaling. Forms DNA complexes activating dendritic cells via TLR9 (\u003cem\u003eNature Medicine\u003c\/em\u003e).\u003c\/p\u003e\n\u003ch3\u003eKey Research Areas\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eAntimicrobial Mechanisms:\u003c\/strong\u003e Broad-spectrum activity against Gram+\/- bacteria, fungi, viruses. Physical mode of action resists pathogen adaptation.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eInnate Immune Signaling:\u003c\/strong\u003e Activates FPRL1, P2X7, EGFR, triggering chemotaxis and cytokine responses bridging innate and adaptive immunity.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWound Healing:\u003c\/strong\u003e EGFR transactivation stimulates keratinocyte migration for re-epithelialization.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBiofilm Research:\u003c\/strong\u003e Anti-biofilm activity at sub-MIC concentrations against P. aeruginosa and S. aureus.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eWhy Researchers Choose Peptides BioLab\u003c\/h3\u003e\n\u003cp\u003eEvery batch of \u003cstrong\u003eLL-37\u003c\/strong\u003e supplied by Peptides BioLab undergoes rigorous HPLC and mass spectrometry analysis, ensuring ≥98% purity verified by an independent Certificate of Analysis (CoA). Our \u003ca href=\"\/products\/ll-37\"\u003eLL-37\u003c\/a\u003e is supplied as a lyophilized powder for maximum stability and shelf life, shipped worldwide from our state-of-the-art facilities in temperature-controlled packaging.\u003c\/p\u003e\n\u003ch3\u003eRelated Research Peptides\u003c\/h3\u003e\n\u003cp\u003eResearchers studying related pathways may also find these compounds relevant: \u003ca href=\"\/products\/kpv\"\u003eKPV\u003c\/a\u003e, \u003ca href=\"\/products\/thymosin-alpha-1\"\u003eThymosin Alpha-1\u003c\/a\u003e, and \u003ca href=\"\/products\/bpc-157\"\u003eBPC-157\u003c\/a\u003e. Browse our \u003ca href=\"\/collections\/recovery\"\u003eImmunomodulatory Research\u003c\/a\u003e collection.\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eFor research purposes only — Not for human consumption. All products are intended solely for in-vitro research and laboratory use.\u003c\/em\u003e\u003c\/p\u003e\n\u003c\/div\u003e","brand":"Peptides BioLab","offers":[{"title":"Default Title","offer_id":60995751739722,"sku":"PBL-LL-37-6G","price":39.99,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0998\/9429\/6906\/files\/peptides-biolab-ll-37-antimicrobial-peptide-5mg-research-grade.webp?v=1773933885"},{"product_id":"kpv","title":"KPV","description":"\u003cdiv class=\"pb-product-desc\"\u003e\n\u003ch2\u003eKPV — Alpha-MSH C-Terminal Tripeptide for Anti-Inflammatory Research\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eKPV\u003c\/strong\u003e (Lys-Pro-Val) is the C-terminal tripeptide of α-MSH, retaining anti-inflammatory properties without melanocortin receptor-mediated melanogenic activity. Characterized by Brzoska et al. (\u003cem\u003eFEBS Letters\u003c\/em\u003e, 1999).\u003c\/p\u003e\n\u003ch3\u003eMechanism of Action\u003c\/h3\u003e\n\u003cp\u003eKPV inhibits NF-κB nuclear translocation by preventing IκBα phosphorylation, suppressing IL-1β, IL-6, and TNF-α. Enters cells directly for receptor-independent effects. Reduces inflammation in colitis models through direct intestinal epithelial cell signaling (\u003cem\u003eJ Immunol\u003c\/em\u003e). Modulates NLRP3 inflammasome.\u003c\/p\u003e\n\u003ch3\u003eKey Research Areas\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eNF-κB Pathway:\u003c\/strong\u003e Inhibits NF-κB at multiple cascade points without broad receptor pharmacology of full-length α-MSH.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIntestinal Inflammation:\u003c\/strong\u003e Demonstrated anti-inflammatory effects in DSS-colitis and IBD models with reduced mucosal damage and neutrophil infiltration.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSkin Inflammation:\u003c\/strong\u003e Reduces IL-8 and TNF-α in UV-irradiated and LPS-stimulated skin cell models.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eInnate Immune Modulation:\u003c\/strong\u003e Modulates macrophage and dendritic cell inflammatory responses while preserving antimicrobial functions.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eWhy Researchers Choose Peptides BioLab\u003c\/h3\u003e\n\u003cp\u003eEvery batch of \u003cstrong\u003eKPV\u003c\/strong\u003e supplied by Peptides BioLab undergoes rigorous HPLC and mass spectrometry analysis, ensuring ≥98% purity verified by an independent Certificate of Analysis (CoA). Our \u003ca href=\"\/products\/kpv\"\u003eKPV\u003c\/a\u003e is supplied as a lyophilized powder for maximum stability and shelf life, shipped worldwide from our state-of-the-art facilities in temperature-controlled packaging.\u003c\/p\u003e\n\u003ch3\u003eRelated Research Peptides\u003c\/h3\u003e\n\u003cp\u003eResearchers studying related pathways may also find these compounds relevant: \u003ca href=\"\/products\/ll-37\"\u003eLL-37\u003c\/a\u003e, \u003ca href=\"\/products\/bpc-157\"\u003eBPC-157\u003c\/a\u003e, and \u003ca href=\"\/products\/thymosin-alpha-1\"\u003eThymosin Alpha-1\u003c\/a\u003e. Browse our \u003ca href=\"\/collections\/recovery\"\u003eImmunomodulatory Research\u003c\/a\u003e collection.\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eFor research purposes only — Not for human consumption. All products are intended solely for in-vitro research and laboratory use.\u003c\/em\u003e\u003c\/p\u003e\n\u003c\/div\u003e","brand":"Peptides BioLab","offers":[{"title":"Default Title","offer_id":60995751772490,"sku":"PBL-KPV-6G","price":59.99,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0998\/9429\/6906\/files\/peptides-biolab-kpv-anti-inflammatory-peptide-10mg-research-grade.webp?v=1773933883"},{"product_id":"thymosin-alpha-1","title":"Thymosin Alpha-1","description":"\u003cdiv class=\"pb-product-desc\"\u003e\n\u003ch2\u003eThymosin Alpha-1 — Thymic Peptide for Dendritic Cell Maturation and Immune Research\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eThymosin Alpha-1\u003c\/strong\u003e (Tα1) is a 28-amino acid thymic peptide (Goldstein et al., 1977). Over 4,400 published articles and 80+ clinical trials. Biological response modifier enhancing innate and adaptive immunity through dendritic cell maturation, T-cell differentiation, and TLR signaling. Approved in 35+ countries.\u003c\/p\u003e\n\u003ch3\u003eMechanism of Action\u003c\/h3\u003e\n\u003cp\u003eTα1 activates TLR2 and TLR9, promoting dendritic cell maturation with increased MHC I\/II, CD80\/CD86, and IL-12 secretion. Drives Th1 differentiation, enhances NK cell cytotoxicity, and stimulates B cell antibody production. Activates p38 MAPK and NF-κB in TLR-dependent manner.\u003c\/p\u003e\n\u003ch3\u003eKey Research Areas\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eDendritic Cell Biology:\u003c\/strong\u003e Promotes DC maturation and functional competence — enhanced antigen processing, MHC expression, T-cell priming.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eT-Cell Differentiation:\u003c\/strong\u003e Drives CD4+ Th1 polarization and enhances CD8+ cytotoxic function — T-cell polarization mechanisms.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTLR Signaling Research:\u003c\/strong\u003e Activates TLR2\/TLR9 — studies how thymic peptides modulate pathogen recognition receptors.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eImmune Senescence:\u003c\/strong\u003e Partially reverses age-associated immune decline, restoring T-cell repertoire diversity and NK function.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eWhy Researchers Choose Peptides BioLab\u003c\/h3\u003e\n\u003cp\u003eEvery batch of \u003cstrong\u003eThymosin Alpha-1\u003c\/strong\u003e supplied by Peptides BioLab undergoes rigorous HPLC and mass spectrometry analysis, ensuring ≥98% purity verified by an independent Certificate of Analysis (CoA). Our \u003ca href=\"\/products\/thymosin-alpha-1\"\u003eThymosin Alpha-1\u003c\/a\u003e is supplied as a lyophilized powder for maximum stability and shelf life, shipped worldwide from our state-of-the-art facilities in temperature-controlled packaging.\u003c\/p\u003e\n\u003ch3\u003eRelated Research Peptides\u003c\/h3\u003e\n\u003cp\u003eResearchers studying related pathways may also find these compounds relevant: \u003ca href=\"\/products\/ll-37\"\u003eLL-37\u003c\/a\u003e, \u003ca href=\"\/products\/kpv\"\u003eKPV\u003c\/a\u003e, and \u003ca href=\"\/products\/tb-500\"\u003eTB-500\u003c\/a\u003e. Browse our \u003ca href=\"\/collections\/recovery\"\u003eImmunomodulatory Research\u003c\/a\u003e collection.\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eFor research purposes only — Not for human consumption. All products are intended solely for in-vitro research and laboratory use.\u003c\/em\u003e\u003c\/p\u003e\n\u003c\/div\u003e","brand":"Peptides BioLab","offers":[{"title":"Default Title","offer_id":60995751805258,"sku":"PBL-THYMOSINALPHA-1-60G","price":79.99,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0998\/9429\/6906\/files\/peptides-biolab-thymosin-alpha-1-immune-peptide-10mg-research-grade.webp?v=1773933903"},{"product_id":"bpc-157-tb-500-ghk-cu-kvp","title":"BPC-157\/TB-500\/GHK-CU\/KVP","description":"\u003cdiv class=\"pb-product-desc\"\u003e\n\u003ch2\u003eBPC-157 \/ TB-500 \/ GHK-Cu \/ KPV Quad Blend — Four-Peptide Formulation for Comprehensive Regenerative Research\u003c\/h2\u003e\n\u003cp\u003eThe \u003cstrong\u003eQuad Blend\u003c\/strong\u003e is the most comprehensive multi-peptide formulation, adding KPV (α-MSH C-terminal tripeptide) for potent NF-κB pathway inhibition. Four-target approach from acute inflammatory modulation through complete tissue regeneration.\u003c\/p\u003e\n\u003ch3\u003eMechanism of Action\u003c\/h3\u003e\n\u003cp\u003eBPC-157 drives VEGF angiogenesis. TB-500 promotes actin-mediated migration. GHK-Cu activates matrix enzymes and stem cell recruitment. KPV directly inhibits NF-κB nuclear translocation, suppressing IL-1β, IL-6, TNF-α and NLRP3 inflammasome — a mechanism not covered by the other three alone.\u003c\/p\u003e\n\u003ch3\u003eKey Research Areas\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eFull-Spectrum Repair Model:\u003c\/strong\u003e Targets inflammation (KPV), angiogenesis (BPC-157), migration (TB-500), matrix remodeling (GHK-Cu) simultaneously.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNF-κB Pathway Integration:\u003c\/strong\u003e KPV's direct NF-κB inhibition complements anti-inflammatory effects of other components.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMucosal and Dermal Models:\u003c\/strong\u003e Each component active in mucosal and dermal contexts — applicable to GI, cutaneous, and musculoskeletal research.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSynergy Assessment:\u003c\/strong\u003e Stepwise dual→triple→quad formulations create a framework for assessing each component's contribution.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eWhy Researchers Choose Peptides BioLab\u003c\/h3\u003e\n\u003cp\u003eEvery batch of \u003cstrong\u003eBPC-157\/TB-500\/GHK-Cu\/KPV Quad Blend\u003c\/strong\u003e supplied by Peptides BioLab undergoes rigorous HPLC and mass spectrometry analysis, ensuring ≥98% purity verified by an independent Certificate of Analysis (CoA). Our \u003ca href=\"\/products\/bpc-157-tb-500-ghk-cu-kvp\"\u003eBPC-157\/TB-500\/GHK-Cu\/KPV Quad Blend\u003c\/a\u003e is supplied as a lyophilized powder for maximum stability and shelf life, shipped worldwide from our state-of-the-art facilities in temperature-controlled packaging.\u003c\/p\u003e\n\u003ch3\u003eRelated Research Peptides\u003c\/h3\u003e\n\u003cp\u003eResearchers studying related pathways may also find these compounds relevant: \u003ca href=\"\/products\/bpc-157-tb-500-ghk-cu\"\u003eBPC-157\/TB-500\/GHK-Cu Triple Blend\u003c\/a\u003e, \u003ca href=\"\/products\/kpv\"\u003eKPV\u003c\/a\u003e, and \u003ca href=\"\/products\/bpc-157-tb-500\"\u003eBPC-157 \u0026amp; TB-500 Blend\u003c\/a\u003e. Browse our \u003ca href=\"\/collections\/peptides-blend\"\u003ePeptide Blends\u003c\/a\u003e collection.\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eFor research purposes only — Not for human consumption. All products are intended solely for in-vitro research and laboratory use.\u003c\/em\u003e\u003c\/p\u003e\n\u003c\/div\u003e","brand":"Peptides BioLab","offers":[{"title":"Default Title","offer_id":60995752821066,"sku":"PBL-BPC-157TB-500GHK-CUKVP-6G","price":199.99,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0998\/9429\/6906\/files\/peptides-biolab-bpc-157-tb-500-ghk-cu-kpv-quad-blend-10mg-research-grade.webp?v=1773935015"},{"product_id":"bpc-157-tb-500-ghk-cu","title":"BPC-157\/TB-500\/GHK-CU","description":"\u003cdiv class=\"pb-product-desc\"\u003e\n\u003ch2\u003eBPC-157 \/ TB-500 \/ GHK-Cu Triple Blend — Three-Peptide Combination for Advanced Regenerative Research\u003c\/h2\u003e\n\u003cp\u003eThe \u003cstrong\u003eTriple Blend\u003c\/strong\u003e adds GHK-Cu (copper tripeptide) to the BPC-157\/TB-500 combination, introducing copper-dependent enzyme activation and ECM remodeling. Each component independently validated in peer-reviewed research. Investigates synergistic effects across angiogenesis, cell migration, collagen synthesis, and stem cell recruitment.\u003c\/p\u003e\n\u003ch3\u003eMechanism of Action\u003c\/h3\u003e\n\u003cp\u003eBPC-157 activates VEGF and FAK-paxillin. TB-500 modulates actin polymerization. GHK-Cu delivers copper for lysyl oxidase, SOD, and stimulates 4,000+ genes. Three-target approach spans inflammation through neovascularization, migration, ECM assembly, and tissue maturation.\u003c\/p\u003e\n\u003ch3\u003eKey Research Areas\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eMulti-Target Regeneration:\u003c\/strong\u003e Simultaneous activation of angiogenic (BPC-157), migratory (TB-500), and matrix-remodeling (GHK-Cu) pathways.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCollagen Architecture:\u003c\/strong\u003e GHK-Cu uniquely contributes copper-dependent collagen cross-linking and matrix maturation.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStem Cell Recruitment:\u003c\/strong\u003e GHK-Cu promotes MSC recruitment while BPC-157 enhances growth factor receptors — enhanced regenerative microenvironment.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWound Healing Research:\u003c\/strong\u003e Each component independently demonstrated in wound closure, granulation, and scar quality models.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eWhy Researchers Choose Peptides BioLab\u003c\/h3\u003e\n\u003cp\u003eEvery batch of \u003cstrong\u003eBPC-157\/TB-500\/GHK-Cu Triple Blend\u003c\/strong\u003e supplied by Peptides BioLab undergoes rigorous HPLC and mass spectrometry analysis, ensuring ≥98% purity verified by an independent Certificate of Analysis (CoA). Our \u003ca href=\"\/products\/bpc-157-tb-500-ghk-cu\"\u003eBPC-157\/TB-500\/GHK-Cu Triple Blend\u003c\/a\u003e is supplied as a lyophilized powder for maximum stability and shelf life, shipped worldwide from our state-of-the-art facilities in temperature-controlled packaging.\u003c\/p\u003e\n\u003ch3\u003eRelated Research Peptides\u003c\/h3\u003e\n\u003cp\u003eResearchers studying related pathways may also find these compounds relevant: \u003ca href=\"\/products\/bpc-157-tb-500\"\u003eBPC-157 \u0026amp; TB-500 Blend\u003c\/a\u003e, \u003ca href=\"\/products\/bpc-157-tb-500-ghk-cu-kvp\"\u003eBPC-157\/TB-500\/GHK-Cu\/KPV Quad Blend\u003c\/a\u003e, and \u003ca href=\"\/products\/ghk-cu\"\u003eGHK-Cu\u003c\/a\u003e. Browse our \u003ca href=\"\/collections\/peptides-blend\"\u003ePeptide Blends\u003c\/a\u003e collection.\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eFor research purposes only — Not for human consumption. All products are intended solely for in-vitro research and laboratory use.\u003c\/em\u003e\u003c\/p\u003e\n\u003c\/div\u003e","brand":"Peptides BioLab","offers":[{"title":"Default Title","offer_id":60995752853834,"sku":"PBL-BPC-157TB-500GHK-CU-6G","price":159.99,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0998\/9429\/6906\/files\/peptides-biolab-bpc-157-tb-500-ghk-cu-triple-blend-10mg-research-grade.webp?v=1773935016"},{"product_id":"ghk-cu","title":"GHK-CU","description":"\u003cdiv class=\"pb-product-desc\"\u003e\n\u003ch2\u003eGHK-Cu — Copper Tripeptide Complex for Regenerative Research\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eGHK-Cu\u003c\/strong\u003e (Glycyl-L-histidyl-L-lysine copper) is a naturally occurring copper-binding tripeptide identified in human plasma by Pickart \u0026amp; Thaler (1973). Over 60 peer-reviewed publications document its roles in wound healing, collagen synthesis, anti-inflammatory signaling, and stem cell recruitment.\u003c\/p\u003e\n\u003ch3\u003eMechanism of Action\u003c\/h3\u003e\n\u003cp\u003eGHK-Cu delivers copper ions essential for lysyl oxidase, SOD, and tyrosinase. It upregulates ECM assembly genes while downregulating metalloproteinases. Genome-wide analysis (\u003cem\u003eGene\u003c\/em\u003e, 2014) revealed modulation of 4,000+ genes across tissue remodeling, inflammation, and antioxidant pathways.\u003c\/p\u003e\n\u003ch3\u003eKey Research Areas\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eWound Healing:\u003c\/strong\u003e Accelerates fibroblast migration and wound closure in scratch assay models. Enhanced granulation tissue and wound tensile strength in vivo.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCollagen \u0026amp; ECM Biology:\u003c\/strong\u003e Stimulates type I\/III collagen, elastin, and proteoglycan synthesis while organizing collagen fibril architecture.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAnti-Inflammatory:\u003c\/strong\u003e Suppresses IL-6, TNF-α, TGF-β1 and reduces oxidative damage markers in tissue injury models.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStem Cell Recruitment:\u003c\/strong\u003e Promotes recruitment and differentiation of mesenchymal stem cells for endogenous regenerative mechanisms.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eWhy Researchers Choose Peptides BioLab\u003c\/h3\u003e\n\u003cp\u003eEvery batch of \u003cstrong\u003eGHK-Cu\u003c\/strong\u003e supplied by Peptides BioLab undergoes rigorous HPLC and mass spectrometry analysis, ensuring ≥98% purity verified by an independent Certificate of Analysis (CoA). Our \u003ca href=\"\/products\/ghk-cu\"\u003eGHK-Cu\u003c\/a\u003e is supplied as a lyophilized powder for maximum stability and shelf life, shipped worldwide from our state-of-the-art facilities in temperature-controlled packaging.\u003c\/p\u003e\n\u003ch3\u003eRelated Research Peptides\u003c\/h3\u003e\n\u003cp\u003eResearchers studying related pathways may also find these compounds relevant: \u003ca href=\"\/products\/ahk-cu\"\u003eAHK-Cu\u003c\/a\u003e, \u003ca href=\"\/products\/bpc-157\"\u003eBPC-157\u003c\/a\u003e, and \u003ca href=\"\/products\/snap-8\"\u003eSNAP-8\u003c\/a\u003e. Browse our \u003ca href=\"\/collections\/anti-aging\"\u003eDermatological Research\u003c\/a\u003e collection.\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eFor research purposes only — Not for human consumption. All products are intended solely for in-vitro research and laboratory use.\u003c\/em\u003e\u003c\/p\u003e\n\u003c\/div\u003e","brand":"Peptides BioLab","offers":[{"title":"50","offer_id":60995753017674,"sku":"PBL-GHK-CU-6G","price":39.99,"currency_code":"EUR","in_stock":true},{"title":"100","offer_id":60995753050442,"sku":"PBL-GHK-CU-6G","price":69.99,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0998\/9429\/6906\/files\/peptides-biolab-ghk-cu-copper-peptide-50mg-research-grade.webp?v=1773933878"},{"product_id":"tb-500","title":"TB-500","description":"\u003cdiv class=\"pb-product-desc\"\u003e\n\u003ch2\u003eTB-500 — Thymosin Beta-4 Active Fragment for Actin Regulation and Tissue Repair Research\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eTB-500\u003c\/strong\u003e (Thymosin Beta-4 Fragment) contains the active region of Tβ4, the primary G-actin sequestering molecule. Promotes cell migration, angiogenesis, and tissue repair. Expressed in virtually all cell types. Research by Goldstein et al. and Sosne et al.\u003c\/p\u003e\n\u003ch3\u003eMechanism of Action\u003c\/h3\u003e\n\u003cp\u003eTB-500 promotes migration via the LKKTET motif, modulating actin polymerization. Upregulates Akt\/PI3K survival signaling, promotes VEGF-dependent and -independent angiogenesis. \u003cem\u003eNature\u003c\/em\u003e (2004) demonstrated functional cardiac regeneration via epicardial cell activation.\u003c\/p\u003e\n\u003ch3\u003eKey Research Areas\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eCell Migration and Wound Healing:\u003c\/strong\u003e Modulates actin dynamics and lamellipodium formation. Accelerated wound closure, enhanced granulation, improved remodeling.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAngiogenesis Research:\u003c\/strong\u003e Promotes new vessel formation through VEGF pathways and direct endothelial cell migration in matrigel assays.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCardiac Regeneration:\u003c\/strong\u003e Landmark: Tβ4 activates epicardial progenitors post-MI, promoting neovascularization and functional recovery.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAnti-Inflammatory Mechanisms:\u003c\/strong\u003e Reduces NF-κB inflammatory gene expression with decreased neutrophil infiltration and pro-inflammatory cytokines.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eWhy Researchers Choose Peptides BioLab\u003c\/h3\u003e\n\u003cp\u003eEvery batch of \u003cstrong\u003eTB-500\u003c\/strong\u003e supplied by Peptides BioLab undergoes rigorous HPLC and mass spectrometry analysis, ensuring ≥98% purity verified by an independent Certificate of Analysis (CoA). Our \u003ca href=\"\/products\/tb-500\"\u003eTB-500\u003c\/a\u003e is supplied as a lyophilized powder for maximum stability and shelf life, shipped worldwide from our state-of-the-art facilities in temperature-controlled packaging.\u003c\/p\u003e\n\u003ch3\u003eRelated Research Peptides\u003c\/h3\u003e\n\u003cp\u003eResearchers studying related pathways may also find these compounds relevant: \u003ca href=\"\/products\/bpc-157\"\u003eBPC-157\u003c\/a\u003e, \u003ca href=\"\/products\/ghk-cu\"\u003eGHK-Cu\u003c\/a\u003e, and \u003ca href=\"\/products\/peg-mgf\"\u003ePEG-MGF\u003c\/a\u003e. Browse our \u003ca href=\"\/collections\/recovery\"\u003eRecovery \u0026amp; Tissue Repair\u003c\/a\u003e collection.\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eFor research purposes only — Not for human consumption. All products are intended solely for in-vitro research and laboratory use.\u003c\/em\u003e\u003c\/p\u003e\n\u003c\/div\u003e","brand":"Peptides BioLab","offers":[{"title":"Default Title","offer_id":60995753640266,"sku":"PBL-TB-500-10MG","price":49.95,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0998\/9429\/6906\/files\/peptides-biolab-tb-500-thymosin-beta-4-peptide-10mg-research-grade.webp?v=1773933902"},{"product_id":"bpc-157","title":"BPC 157","description":"\u003cdiv class=\"pb-product-desc\"\u003e\n\u003ch2\u003eBPC-157 — Gastric Pentadecapeptide for Tissue Repair and Cytoprotection Research\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eBPC-157\u003c\/strong\u003e (Body Protection Compound-157) is a synthetic 15-amino acid peptide derived from human gastric juice. Characterized by Sikiric et al. at the University of Zagreb, it has over 100 published preclinical studies on tissue repair, angiogenesis, and cytoprotection. Notable for stability in acidic environments and broad biological activity across organ systems.\u003c\/p\u003e\n\u003ch3\u003eMechanism of Action\u003c\/h3\u003e\n\u003cp\u003eBPC-157 modulates the NO system and upregulates VEGF, FGF-2, and EGF receptor signaling. It promotes angiogenesis via endothelial cell migration and tube formation (\u003cem\u003eCurrent Pharmaceutical Design\u003c\/em\u003e, 2018). It interacts with dopaminergic and serotonergic systems, and activates the FAK-paxillin pathway for fibroblast migration.\u003c\/p\u003e\n\u003ch3\u003eKey Research Areas\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eTendon and Ligament Research:\u003c\/strong\u003e Accelerates tendon-to-bone healing with improved collagen fiber organization and mechanical strength in rat models.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGastrointestinal Cytoprotection:\u003c\/strong\u003e Protective effects against NSAID-induced lesions, ethanol damage, and surgical anastomosis complications.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAngiogenesis and Wound Healing:\u003c\/strong\u003e Stimulates blood vessel formation and granulation tissue development, accelerating wound closure.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNeuroprotective Pathways:\u003c\/strong\u003e Modulates neurotransmitter systems and protects against peripheral nerve crush injury.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eWhy Researchers Choose Peptides BioLab\u003c\/h3\u003e\n\u003cp\u003eEvery batch of \u003cstrong\u003eBPC-157\u003c\/strong\u003e supplied by Peptides BioLab undergoes rigorous HPLC and mass spectrometry analysis, ensuring ≥98% purity verified by an independent Certificate of Analysis (CoA). Our \u003ca href=\"\/products\/bpc-157\"\u003eBPC-157\u003c\/a\u003e is supplied as a lyophilized powder for maximum stability and shelf life, shipped worldwide from our state-of-the-art facilities in temperature-controlled packaging.\u003c\/p\u003e\n\u003ch3\u003eRelated Research Peptides\u003c\/h3\u003e\n\u003cp\u003eResearchers studying related pathways may also find these compounds relevant: \u003ca href=\"\/products\/tb-500\"\u003eTB-500\u003c\/a\u003e, \u003ca href=\"\/products\/ghk-cu\"\u003eGHK-Cu\u003c\/a\u003e, and \u003ca href=\"\/products\/kpv\"\u003eKPV\u003c\/a\u003e. Browse our \u003ca href=\"\/collections\/recovery\"\u003eRecovery \u0026amp; Tissue Repair\u003c\/a\u003e collection.\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eFor research purposes only — Not for human consumption. All products are intended solely for in-vitro research and laboratory use.\u003c\/em\u003e\u003c\/p\u003e\n\u003c\/div\u003e","brand":"Peptides BioLab","offers":[{"title":"Default Title","offer_id":60995753673034,"sku":"PBL-BPC157-10MG","price":39.99,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0998\/9429\/6906\/files\/peptides-biolab-bpc-157-peptide-10mg-research-grade.webp?v=1773933875"},{"product_id":"bpc-157-tb-500","title":"BPC 157 | TB 500","description":"\u003cdiv class=\"pb-product-desc\"\u003e\n\u003ch2\u003eBPC-157 \u0026amp; TB-500 Blend — Dual-Peptide Combination for Synergistic Tissue Repair Research\u003c\/h2\u003e\n\u003cp\u003eThe \u003cstrong\u003eBPC-157 \u0026amp; TB-500 Blend\u003c\/strong\u003e combines two of the most studied tissue repair peptides. BPC-157 is a gastric pentadecapeptide with angiogenic and cytoprotective properties. TB-500 is the primary G-actin sequestering peptide promoting cell migration and cytoskeletal reorganization. Complementary mechanisms for wound healing, angiogenesis, and inflammation resolution.\u003c\/p\u003e\n\u003ch3\u003eMechanism of Action\u003c\/h3\u003e\n\u003cp\u003eBPC-157 activates VEGF and FAK-paxillin signaling. TB-500 modulates actin polymerization via the LKKTET motif. BPC-157 upregulates growth factor receptors (VEGFR2, EGF-R), potentially enhancing cellular response to TB-500's migratory signals. Together they address inflammation resolution, neovascularization, cell migration, and ECM remodeling.\u003c\/p\u003e\n\u003ch3\u003eKey Research Areas\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eComplementary Angiogenic Pathways:\u003c\/strong\u003e BPC-157 drives VEGF-dependent angiogenesis while TB-500 promotes endothelial migration — vessel formation at signaling and structural levels.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMulti-Phase Tissue Repair:\u003c\/strong\u003e Both peptides span inflammatory, proliferative, and remodeling phases. Studies potential synergistic effects across all repair phases.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTendon and Connective Tissue:\u003c\/strong\u003e Both independently demonstrate tendon healing effects. Combination investigates dual-pathway additive or synergistic improvements.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eInflammatory Resolution:\u003c\/strong\u003e Both reduce NF-κB signaling and pro-inflammatory cytokines through distinct molecular mechanisms.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eWhy Researchers Choose Peptides BioLab\u003c\/h3\u003e\n\u003cp\u003eEvery batch of \u003cstrong\u003eBPC-157 \u0026amp; TB-500 Blend\u003c\/strong\u003e supplied by Peptides BioLab undergoes rigorous HPLC and mass spectrometry analysis, ensuring ≥98% purity verified by an independent Certificate of Analysis (CoA). Our \u003ca href=\"\/products\/bpc-157-tb-500\"\u003eBPC-157 \u0026amp; TB-500 Blend\u003c\/a\u003e is supplied as a lyophilized powder for maximum stability and shelf life, shipped worldwide from our state-of-the-art facilities in temperature-controlled packaging.\u003c\/p\u003e\n\u003ch3\u003eRelated Research Peptides\u003c\/h3\u003e\n\u003cp\u003eResearchers studying related pathways may also find these compounds relevant: \u003ca href=\"\/products\/bpc-157\"\u003eBPC-157\u003c\/a\u003e, \u003ca href=\"\/products\/tb-500\"\u003eTB-500\u003c\/a\u003e, and \u003ca href=\"\/products\/bpc-157-tb-500-ghk-cu\"\u003eBPC-157\/TB-500\/GHK-Cu Triple Blend\u003c\/a\u003e. Browse our \u003ca href=\"\/collections\/recovery\"\u003eRecovery \u0026amp; Tissue Repair\u003c\/a\u003e collection.\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eFor research purposes only — Not for human consumption. All products are intended solely for in-vitro research and laboratory use.\u003c\/em\u003e\u003c\/p\u003e\n\u003c\/div\u003e","brand":"Peptides BioLab","offers":[{"title":"10","offer_id":60995753738570,"sku":"PBL-BPC157TB500-10MG","price":69.99,"currency_code":"EUR","in_stock":true},{"title":"20","offer_id":60995753771338,"sku":"PBL-BPC157TB500-10MG","price":129.99,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0998\/9429\/6906\/files\/peptides-biolab-bpc-157-tb-500-blend-peptide-10mg-research-grade.webp?v=1773933876"},{"product_id":"tb-500-fragment","title":"TB-500 Fragment","description":"\u003cdiv class=\"pb-product-desc\"\u003e\n\u003ch2\u003eTB-500 Fragment — Active Core Sequence of Thymosin Beta-4 for Targeted Tissue Repair Research\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eTB-500 Fragment\u003c\/strong\u003e is a synthetic peptide corresponding to the active region (amino acids 17-23, Ac-SDKP) of Thymosin Beta-4 (Tβ4), a 43-amino acid polypeptide originally isolated from the thymus gland. While full-length TB-500 has been widely studied for its tissue repair and anti-inflammatory properties, this fragment isolates the minimum pharmacophoric sequence responsible for the compound's principal biological activities: actin sequestration, cell migration promotion, and anti-fibrotic signaling. This targeted fragment allows researchers to investigate structure-activity relationships within the Tβ4 sequence with greater molecular precision.\u003c\/p\u003e\n\n\u003ch3\u003eMechanism of Action\u003c\/h3\u003e\n\u003cp\u003eThe \u003cstrong\u003eTB-500 Fragment\u003c\/strong\u003e retains the core Ac-SDKP tetrapeptide motif that interacts with G-actin monomers, modulating actin polymerization dynamics. By sequestering G-actin, the fragment influences lamellipodia formation and directional cell migration. Published studies in \u003cem\u003eAnnals of the New York Academy of Sciences\u003c\/em\u003e have demonstrated that this active sequence promotes endothelial cell migration and tubulogenesis through upregulation of VEGF and Ang-1 expression. Additionally, Ac-SDKP has been shown to inhibit TGF-β\/Smad signaling, reducing collagen I and III deposition by activated fibroblasts, which underlies its anti-fibrotic properties observed in preclinical cardiac and renal fibrosis models.\u003c\/p\u003e\n\n\u003ch3\u003eKey Research Areas\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eTissue Repair Mechanisms:\u003c\/strong\u003e Researchers have utilized \u003cstrong\u003eTB-500 Fragment\u003c\/strong\u003e to study the minimal structural requirements for Tβ4-mediated tissue repair, demonstrating that the Ac-SDKP core sequence is sufficient to promote keratinocyte and fibroblast migration in wound healing assays.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAnti-Fibrotic Pathways:\u003c\/strong\u003e Published studies in \u003cem\u003eKidney International\u003c\/em\u003e have shown that Ac-SDKP inhibits renal fibrosis progression by suppressing TGF-β1\/Smad3 signaling and reducing α-SMA expression in myofibroblasts, establishing a model for anti-fibrotic compound evaluation.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAngiogenesis Research:\u003c\/strong\u003e The fragment has been studied in chorioallantoic membrane (CAM) and Matrigel plug assays, demonstrating pro-angiogenic activity through enhanced endothelial cell proliferation, migration, and capillary network formation.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCardiac Injury Models:\u003c\/strong\u003e Investigators have examined TB-500 Fragment's effects in murine myocardial infarction models, documenting reduced scar formation and improved cardiac function parameters, with mechanism studies pointing to both anti-inflammatory and pro-survival signaling.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003eWhy Researchers Choose Peptides BioLab\u003c\/h3\u003e\n\u003cp\u003eEvery batch of \u003cstrong\u003eTB-500 Fragment\u003c\/strong\u003e supplied by Peptides BioLab undergoes rigorous HPLC and mass spectrometry analysis, ensuring ≥98% purity verified by an independent Certificate of Analysis (CoA). Our \u003ca href=\"\/products\/tb-500-fragment\"\u003eTB-500 Fragment\u003c\/a\u003e is supplied as a lyophilized powder for maximum stability and shelf life, shipped worldwide from our state-of-the-art facilities in temperature-controlled packaging.\u003c\/p\u003e\n\n\u003ch3\u003eRelated Research Peptides\u003c\/h3\u003e\n\u003cp\u003eResearchers studying tissue repair and regenerative pathways may also find these compounds relevant: \u003ca href=\"\/products\/tb-500\"\u003eTB-500\u003c\/a\u003e, \u003ca href=\"\/products\/bpc-157\"\u003eBPC-157\u003c\/a\u003e, and \u003ca href=\"\/products\/ghk-cu\"\u003eGHK-Cu\u003c\/a\u003e. For a complete overview, browse our \u003ca href=\"\/collections\/recovery\"\u003eRecovery Research\u003c\/a\u003e collection.\u003c\/p\u003e\n\n\u003cp\u003e\u003cem\u003eFor research purposes only — Not for human consumption. All products are intended solely for in-vitro research and laboratory use.\u003c\/em\u003e\u003c\/p\u003e\n\u003c\/div\u003e","brand":"Peptides BioLab","offers":[{"title":"Default Title","offer_id":61420647121226,"sku":"PBL-TB500-FRAG-10MG","price":39.99,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0998\/9429\/6906\/files\/peptides-biolab-tb-500-fragment-10mg-research-grade.webp?v=1774393548"},{"product_id":"thymalin","title":"Thymalin","description":"\u003cdiv class=\"pb-product-desc\"\u003e\n\u003ch2\u003eThymalin — Thymic Bioregulatory Peptide for Immunomodulation and Aging Research\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eThymalin\u003c\/strong\u003e (also known as Thymaline) is a polypeptide complex originally isolated from the thymus gland, developed by Professor Vladimir Khavinson at the St. Petersburg Institute of Bioregulation and Gerontology. As one of the foundational compounds in the Khavinson bioregulatory peptide paradigm, Thymalin has been the subject of over 40 years of research, with more than 100 published studies documenting its immunomodulatory and geroprotective properties. The compound acts on thymic epithelial cells and T-lymphocyte precursors, restoring immune function parameters that decline with age-related thymic involution.\u003c\/p\u003e\n\n\u003ch3\u003eMechanism of Action\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eThymalin\u003c\/strong\u003e acts on the neuroendocrine-immune regulatory axis by modulating thymic microenvironment signaling. Published research in \u003cem\u003eBulletin of Experimental Biology and Medicine\u003c\/em\u003e has demonstrated that Thymalin restores the balance between T-helper and T-suppressor lymphocyte populations, normalizes IL-2 receptor expression on T-cells, and stimulates thymulin (FTS) secretion from thymic epithelial cells. The compound also modulates the hypothalamic-pituitary-thymic axis, with studies showing restoration of melatonin and cortisol circadian rhythmicity in aged animal models. Additionally, Khavinson's research published in \u003cem\u003eAdvances in Gerontology\u003c\/em\u003e demonstrated that Thymalin influences telomerase activity in immune cells, potentially counteracting replicative senescence in the lymphocyte compartment.\u003c\/p\u003e\n\n\u003ch3\u003eKey Research Areas\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eImmune Restoration:\u003c\/strong\u003e Clinical studies involving over 300 participants published by Khavinson and colleagues demonstrated that \u003cstrong\u003eThymalin\u003c\/strong\u003e administration restored T-cell immunity indices in elderly subjects, normalizing CD4\/CD8 ratios and enhancing natural killer cell cytotoxicity, establishing it as a reference compound for immune aging research.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGeroprotection:\u003c\/strong\u003e A landmark 15-year observational study published in \u003cem\u003eBulletin of Experimental Biology and Medicine\u003c\/em\u003e (2003) documented a 28% reduction in cardiovascular mortality and a 2.0-fold reduction in overall mortality rate in elderly patients who received periodic Thymalin and Epithalon treatment courses.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eThymic Involution:\u003c\/strong\u003e Researchers have utilized Thymalin to study the mechanisms of age-related thymic atrophy, demonstrating partial reversal of thymic involution markers including restoration of cortical-medullary architecture and thymocyte populations in aged rodent models.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNeuroimmune Crosstalk:\u003c\/strong\u003e Published studies have examined how Thymalin modulates the bidirectional communication between the immune and nervous systems, documenting effects on pineal melatonin synthesis, cortisol rhythmicity, and neuropeptide expression patterns in hypothalamic nuclei.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003eWhy Researchers Choose Peptides BioLab\u003c\/h3\u003e\n\u003cp\u003eEvery batch of \u003cstrong\u003eThymalin\u003c\/strong\u003e supplied by Peptides BioLab undergoes rigorous HPLC and mass spectrometry analysis, ensuring ≥98% purity verified by an independent Certificate of Analysis (CoA). Our \u003ca href=\"\/products\/thymalin\"\u003eThymalin\u003c\/a\u003e is supplied as a lyophilized powder for maximum stability and shelf life, shipped worldwide from our state-of-the-art facilities in temperature-controlled packaging.\u003c\/p\u003e\n\n\u003ch3\u003eRelated Research Peptides\u003c\/h3\u003e\n\u003cp\u003eResearchers studying bioregulatory peptides and immunomodulation may also find these compounds relevant: \u003ca href=\"\/products\/epithalon\"\u003eEpithalon\u003c\/a\u003e, \u003ca href=\"\/products\/thymosin-alpha-1\"\u003eThymosin Alpha-1\u003c\/a\u003e, and \u003ca href=\"\/products\/bpc-157\"\u003eBPC-157\u003c\/a\u003e. For a complete overview, browse our \u003ca href=\"\/collections\/recovery\"\u003eRecovery Research\u003c\/a\u003e collection.\u003c\/p\u003e\n\n\u003cp\u003e\u003cem\u003eFor research purposes only — Not for human consumption. All products are intended solely for in-vitro research and laboratory use.\u003c\/em\u003e\u003c\/p\u003e\n\u003c\/div\u003e","brand":"Peptides BioLab","offers":[{"title":"Default Title","offer_id":61420648366410,"sku":"PBL-THYMALIN-10MG","price":29.99,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0998\/9429\/6906\/files\/peptides-biolab-thymalin-peptide-10mg-research-grade.webp?v=1774393555"},{"product_id":"vilon","title":"Vilon","description":"\u003cdiv class=\"pb-product-desc\"\u003e\n\u003ch2\u003eVilon (Lys-Glu) — Thymic Dipeptide Bioregulator for Immune Research\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eVilon\u003c\/strong\u003e (Lys-Glu) is a synthetic dipeptide bioregulator developed at the St. Petersburg Institute of Bioregulation and Gerontology under the direction of Professor Vladimir Khavinson. As the shortest known peptide with demonstrated immunomodulatory activity, Vilon has been the subject of extensive research published in \u003cem\u003eBulletin of Experimental Biology and Medicine\u003c\/em\u003e and other peer-reviewed journals. This dipeptide mimics the regulatory activity of thymic peptide extracts, modulating T-lymphocyte differentiation and immune function at remarkably low concentrations.\u003c\/p\u003e\n\n\u003ch3\u003eMechanism of Action\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eVilon\u003c\/strong\u003e interacts with specific DNA sequences in the promoter regions of genes involved in immune regulation, particularly those governing T-cell differentiation and cytokine production. Research has demonstrated that the Lys-Glu dipeptide binds to the minor groove of double-stranded DNA, modulating chromatin conformation and transcription factor accessibility. This epigenetic mechanism allows Vilon to regulate gene expression without direct receptor-mediated signaling, a hallmark of Khavinson's bioregulator peptide class.\u003c\/p\u003e\n\n\u003ch3\u003eKey Research Areas\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eT-Cell Differentiation:\u003c\/strong\u003e In-vitro studies have demonstrated that \u003cstrong\u003eVilon\u003c\/strong\u003e promotes CD4+ and CD8+ T-lymphocyte maturation from thymocyte precursors, restoring thymic output parameters in aged animal models to levels comparable to younger controls.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eImmunosenescence:\u003c\/strong\u003e Research on aged rodent models has shown that Vilon administration normalizes the CD4\/CD8 ratio, restores delayed-type hypersensitivity responses, and enhances natural killer cell cytotoxicity against tumor target cells.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGene Expression Modulation:\u003c\/strong\u003e Microarray studies have identified Vilon-responsive gene clusters involved in immune surveillance, apoptosis regulation, and antioxidant defense, demonstrating broad transcriptomic effects from a minimal peptide structure.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSynergistic Bioregulation:\u003c\/strong\u003e Combined treatment with Vilon and \u003ca href=\"\/products\/epitalon\"\u003eEpitalon\u003c\/a\u003e has shown enhanced immune restoration effects in preclinical models, suggesting complementary mechanisms between thymic and pineal bioregulators.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003eTechnical Specifications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eDosage per vial:\u003c\/strong\u003e 10mg lyophilized powder\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity:\u003c\/strong\u003e ≥98% (HPLC verified)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSequence:\u003c\/strong\u003e Lys-Glu (KE dipeptide)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Weight:\u003c\/strong\u003e 275.30 Da\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStorage:\u003c\/strong\u003e -20°C, protected from light\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003eWhy Researchers Choose Peptides BioLab\u003c\/h3\u003e\n\u003cp\u003eEvery batch of \u003cstrong\u003eVilon\u003c\/strong\u003e supplied by Peptides BioLab undergoes rigorous HPLC and mass spectrometry analysis, ensuring ≥98% purity verified by an independent Certificate of Analysis (CoA). Our product is supplied as a lyophilized powder for maximum stability, shipped worldwide in temperature-controlled packaging.\u003c\/p\u003e\n\n\u003ch3\u003eRelated Research Peptides\u003c\/h3\u003e\n\u003cp\u003eResearchers studying thymic bioregulation and immunology may also find these compounds relevant: \u003ca href=\"\/products\/thymalin\"\u003eThymalin\u003c\/a\u003e, \u003ca href=\"\/products\/thymosin-alpha-1\"\u003eThymosin Alpha-1\u003c\/a\u003e, and \u003ca href=\"\/products\/ll-37\"\u003eLL-37\u003c\/a\u003e. For a complete overview, browse our \u003ca href=\"\/collections\/recovery\"\u003eRecovery Research\u003c\/a\u003e collection.\u003c\/p\u003e\n\n\u003cp\u003e\u003cem\u003eFor research purposes only — Not for human consumption. All products are intended solely for in-vitro research and laboratory use.\u003c\/em\u003e\u003c\/p\u003e\n\u003c\/div\u003e","brand":"Peptides BioLab","offers":[{"title":"Default Title","offer_id":61420737626442,"sku":"PBL-VILON-10MG","price":29.99,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0998\/9429\/6906\/files\/peptides-biolab-vilon-bioregulator-peptide-10mg-research-grade.webp?v=1774393564"},{"product_id":"pnc-27","title":"PNC-27","description":"\u003cdiv class=\"pb-product-desc\"\u003e\n\u003ch2\u003ePNC-27 — p53-Derived Membrane-Active Peptide for Cancer Biology Research\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003ePNC-27\u003c\/strong\u003e is a synthetic peptide derived from a segment of the p53 tumor suppressor protein (residues 12-26) fused to a transmembrane-penetrating sequence from the HDM-2 binding domain. Developed and characterized by Kanovsky et al. (2001) in \u003cem\u003eProceedings of the National Academy of Sciences\u003c\/em\u003e, PNC-27 has been shown to selectively bind to HDM-2 protein overexpressed on the surface of transformed cells, inducing rapid membranolysis through pore formation. This selectivity for malignant cells makes \u003cstrong\u003ePNC-27\u003c\/strong\u003e a unique tool for studying membrane dynamics and tumor-specific targeting strategies.\u003c\/p\u003e\n\n\u003ch3\u003eMechanism of Action\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003ePNC-27\u003c\/strong\u003e exploits the abnormal cell-surface expression of HDM-2 (human double minute 2) found on many transformed cell types. In non-malignant cells, HDM-2 is an intracellular protein that regulates p53 degradation via ubiquitination. However, in transformed cells, HDM-2 translocates to the outer membrane leaflet. PNC-27 binds this surface-exposed HDM-2 with high affinity, oligomerizes within the lipid bilayer, and forms transmembrane pores that cause rapid cell lysis. This mechanism operates independently of caspase-dependent apoptosis, inducing necrotic cell death within minutes of membrane engagement.\u003c\/p\u003e\n\n\u003ch3\u003eKey Research Areas\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSelective Membranolysis:\u003c\/strong\u003e In-vitro studies across multiple cancer cell lines (MDA-MB-231, MCF-7, PANC-1) have demonstrated that \u003cstrong\u003ePNC-27\u003c\/strong\u003e induces rapid membrane destruction in transformed cells while leaving non-malignant control cells (HEK-293, primary fibroblasts) viable at equivalent concentrations.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHDM-2 Surface Biology:\u003c\/strong\u003e PNC-27 has served as a probe for mapping HDM-2 externalization patterns, revealing that surface expression correlates with degree of malignant transformation and can be detected by flow cytometry using fluorescently labeled PNC-27 conjugates.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCombination Studies:\u003c\/strong\u003e Research has investigated PNC-27 in combination with conventional chemotherapeutics, with published data suggesting synergistic cytotoxicity when paired with cisplatin or gemcitabine in pancreatic cancer models.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMembrane Pore Dynamics:\u003c\/strong\u003e Biophysical studies using artificial lipid bilayers have characterized PNC-27 pore formation kinetics, providing insights into peptide-membrane interaction mechanisms relevant to antimicrobial peptide design.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003eTechnical Specifications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eDosage per vial:\u003c\/strong\u003e 5mg lyophilized powder\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity:\u003c\/strong\u003e ≥98% (HPLC verified)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStorage:\u003c\/strong\u003e -20°C, protected from light\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003eWhy Researchers Choose Peptides BioLab\u003c\/h3\u003e\n\u003cp\u003eEvery batch of \u003cstrong\u003ePNC-27\u003c\/strong\u003e supplied by Peptides BioLab undergoes rigorous HPLC and mass spectrometry analysis, ensuring ≥98% purity verified by an independent Certificate of Analysis (CoA). Our product is supplied as a lyophilized powder for maximum stability, shipped worldwide in temperature-controlled packaging.\u003c\/p\u003e\n\n\u003ch3\u003eRelated Research Peptides\u003c\/h3\u003e\n\u003cp\u003eResearchers studying anti-tumor peptides and membrane biology may also find these compounds relevant: \u003ca href=\"\/products\/ll-37\"\u003eLL-37\u003c\/a\u003e, \u003ca href=\"\/products\/thymosin-alpha-1\"\u003eThymosin Alpha-1\u003c\/a\u003e, and \u003ca href=\"\/products\/bpc-157\"\u003eBPC-157\u003c\/a\u003e. For a complete overview, browse our \u003ca href=\"\/collections\/recovery\"\u003eRecovery Research\u003c\/a\u003e collection.\u003c\/p\u003e\n\n\u003cp\u003e\u003cem\u003eFor research purposes only — Not for human consumption. All products are intended solely for in-vitro research and laboratory use.\u003c\/em\u003e\u003c\/p\u003e\n\u003c\/div\u003e","brand":"Peptides BioLab","offers":[{"title":"Default Title","offer_id":61420737659210,"sku":"PBL-PNC27-5MG","price":44.99,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0998\/9429\/6906\/files\/peptides-biolab-pnc-27-peptide-5mg-research-grade.webp?v=1774393566"},{"product_id":"bronchogen","title":"Bronchogen","description":"\u003cdiv class=\"pb-product-desc\"\u003e\n\u003ch2\u003eBronchogen (Ala-Glu-Asp) — Bronchial Bioregulator Peptide for Pulmonary Research\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eBronchogen\u003c\/strong\u003e is a synthetic tripeptide bioregulator (Ala-Glu-Asp) developed at the St. Petersburg Institute of Bioregulation and Gerontology under the direction of Professor Vladimir Khavinson. This short peptide belongs to the Khavinson class of tissue-specific bioregulators that modulate gene expression through direct DNA interaction. Bronchogen has been specifically characterized for its regulatory effects on bronchial mucosa and respiratory epithelium, with research published in \u003cem\u003eBulletin of Experimental Biology and Medicine\u003c\/em\u003e documenting its capacity to normalize respiratory tissue function in aged and compromised animal models.\u003c\/p\u003e\n\n\u003ch3\u003eMechanism of Action\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eBronchogen\u003c\/strong\u003e interacts with specific nucleotide sequences in promoter regions of genes expressed in bronchial epithelial tissue. This short bioregulator peptide penetrates cell membranes and binds the minor groove of double-stranded DNA, modulating chromatin accessibility and transcription factor binding at target gene loci. Research has demonstrated that Bronchogen upregulates the expression of surfactant proteins (SP-A, SP-D), mucin regulatory genes, and anti-inflammatory mediators in bronchial tissue cultures, while normalizing ciliary beat frequency in airway epithelial cell monolayers.\u003c\/p\u003e\n\n\u003ch3\u003eKey Research Areas\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eBronchial Epithelial Regeneration:\u003c\/strong\u003e Studies on human bronchial epithelial cell cultures have demonstrated that \u003cstrong\u003eBronchogen\u003c\/strong\u003e enhances proliferative capacity and restores tight junction protein expression (claudin-1, occludin) following chemical injury, suggesting accelerated mucosal barrier repair.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMucociliary Function:\u003c\/strong\u003e Research in aged murine respiratory explants has shown normalization of ciliary beat frequency and mucus transport velocity following Bronchogen treatment, restoring parameters to levels observed in young control tissue.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAnti-Inflammatory Modulation:\u003c\/strong\u003e In-vitro studies have documented reduced IL-8 and TNF-α secretion from LPS-stimulated bronchial epithelial cells treated with Bronchogen, while preserving baseline immune surveillance capacity.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAge-Related Pulmonary Decline:\u003c\/strong\u003e Long-term studies in aged rodent models have observed preserved alveolar architecture and maintained gas exchange efficiency, with histological analysis showing reduced emphysematous changes compared to untreated controls.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003eTechnical Specifications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eDosage per vial:\u003c\/strong\u003e 10mg lyophilized powder\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity:\u003c\/strong\u003e ≥98% (HPLC verified)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSequence:\u003c\/strong\u003e Ala-Glu-Asp (AED tripeptide)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Weight:\u003c\/strong\u003e 333.29 Da\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStorage:\u003c\/strong\u003e -20°C, protected from light\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003eWhy Researchers Choose Peptides BioLab\u003c\/h3\u003e\n\u003cp\u003eEvery batch of \u003cstrong\u003eBronchogen\u003c\/strong\u003e supplied by Peptides BioLab undergoes rigorous HPLC and mass spectrometry analysis, ensuring ≥98% purity verified by an independent Certificate of Analysis (CoA). Our product is supplied as a lyophilized powder for maximum stability, shipped worldwide in temperature-controlled packaging.\u003c\/p\u003e\n\n\u003ch3\u003eRelated Research Peptides\u003c\/h3\u003e\n\u003cp\u003eResearchers studying Khavinson bioregulators and tissue repair may also find these compounds relevant: \u003ca href=\"\/products\/thymalin\"\u003eThymalin\u003c\/a\u003e, \u003ca href=\"\/products\/bpc-157\"\u003eBPC-157\u003c\/a\u003e, and \u003ca href=\"\/products\/kpv\"\u003eKPV\u003c\/a\u003e. For a complete overview, browse our \u003ca href=\"\/collections\/recovery\"\u003eRecovery Research\u003c\/a\u003e collection.\u003c\/p\u003e\n\n\u003cp\u003e\u003cem\u003eFor research purposes only — Not for human consumption. All products are intended solely for in-vitro research and laboratory use.\u003c\/em\u003e\u003c\/p\u003e\n\u003c\/div\u003e","brand":"Peptides BioLab","offers":[{"title":"Default Title","offer_id":61420760564042,"sku":"PBL-BRONCHOGEN-10MG","price":29.99,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0998\/9429\/6906\/files\/peptides-biolab-bronchogen-bioregulator-peptide-10mg-research-grade.webp?v=1774393575"},{"product_id":"cardiogen","title":"Cardiogen","description":"\u003cdiv class=\"pb-product-desc\"\u003e\n\u003ch2\u003eCardiogen (Ala-Glu-Asp-Arg) — Cardiac Bioregulator Peptide for Cardiovascular Research\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eCardiogen\u003c\/strong\u003e is a synthetic tetrapeptide bioregulator (Ala-Glu-Asp-Arg) developed at the St. Petersburg Institute of Bioregulation and Gerontology by Professor Vladimir Khavinson's research group. As a cardiac-specific bioregulator, Cardiogen has been characterized for its regulatory effects on myocardial gene expression and cardiomyocyte function. Published research in \u003cem\u003eBulletin of Experimental Biology and Medicine\u003c\/em\u003e has demonstrated its capacity to normalize contractile function, restore metabolic enzyme expression, and promote cardiac tissue resilience in aged and ischemia-damaged myocardial models.\u003c\/p\u003e\n\n\u003ch3\u003eMechanism of Action\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eCardiogen\u003c\/strong\u003e operates via the characteristic Khavinson bioregulator mechanism—direct interaction with specific DNA sequences to modulate gene transcription in target tissues. The AEDR tetrapeptide binds complementary nucleotide sequences in promoter regions of cardiac-specific genes, including those encoding myosin heavy chain isoforms, troponin complex subunits, and mitochondrial respiratory chain enzymes. Research has demonstrated selective upregulation of cardioprotective heat shock proteins (HSP70, HSP27) and anti-apoptotic Bcl-2 family members in cardiomyocyte cultures.\u003c\/p\u003e\n\n\u003ch3\u003eKey Research Areas\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eMyocardial Protection:\u003c\/strong\u003e In-vitro studies on isolated cardiomyocyte preparations have demonstrated that \u003cstrong\u003eCardiogen\u003c\/strong\u003e preserves contractile function and reduces lactate dehydrogenase release following simulated ischemia-reperfusion injury, suggesting direct cardioprotective activity.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCardiac Aging:\u003c\/strong\u003e Research in aged rodent models has shown that Cardiogen administration restores myocardial compliance parameters, normalizes diastolic filling indices, and preserves mitochondrial ultrastructure in cardiac tissue.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGene Expression Normalization:\u003c\/strong\u003e Microarray analysis of Cardiogen-treated cardiac tissue has revealed restored expression of age-dysregulated genes involved in calcium handling (SERCA2a, phospholamban), energy metabolism (CPT-1, PDH), and antioxidant defense.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFibrosis Modulation:\u003c\/strong\u003e Histological studies have documented reduced interstitial fibrosis and preserved capillary density in aged myocardium following chronic Cardiogen treatment, correlating with maintained TGF-β1\/Smad signaling homeostasis.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003eTechnical Specifications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eDosage per vial:\u003c\/strong\u003e 10mg lyophilized powder\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity:\u003c\/strong\u003e ≥98% (HPLC verified)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSequence:\u003c\/strong\u003e Ala-Glu-Asp-Arg (AEDR tetrapeptide)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Weight:\u003c\/strong\u003e 489.48 Da\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStorage:\u003c\/strong\u003e -20°C, protected from light\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003eWhy Researchers Choose Peptides BioLab\u003c\/h3\u003e\n\u003cp\u003eEvery batch of \u003cstrong\u003eCardiogen\u003c\/strong\u003e supplied by Peptides BioLab undergoes rigorous HPLC and mass spectrometry analysis, ensuring ≥98% purity verified by an independent Certificate of Analysis (CoA). Our product is supplied as a lyophilized powder for maximum stability, shipped worldwide in temperature-controlled packaging.\u003c\/p\u003e\n\n\u003ch3\u003eRelated Research Peptides\u003c\/h3\u003e\n\u003cp\u003eResearchers studying cardiac bioregulation and cardiovascular peptides may also find these compounds relevant: \u003ca href=\"\/products\/thymalin\"\u003eThymalin\u003c\/a\u003e, \u003ca href=\"\/products\/bpc-157\"\u003eBPC-157\u003c\/a\u003e, and \u003ca href=\"\/products\/ss-31\"\u003eSS-31\u003c\/a\u003e. For a complete overview, browse our \u003ca href=\"\/collections\/recovery\"\u003eRecovery Research\u003c\/a\u003e collection.\u003c\/p\u003e\n\n\u003cp\u003e\u003cem\u003eFor research purposes only — Not for human consumption. All products are intended solely for in-vitro research and laboratory use.\u003c\/em\u003e\u003c\/p\u003e\n\u003c\/div\u003e","brand":"Peptides BioLab","offers":[{"title":"Default Title","offer_id":61420760793418,"sku":"PBL-CARDIOGEN-10MG","price":29.99,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0998\/9429\/6906\/files\/peptides-biolab-cardiogen-bioregulator-peptide-10mg-research-grade.webp?v=1774393577"},{"product_id":"livagen","title":"Livagen","description":"\u003cdiv class=\"pb-product-desc\"\u003e\n\u003ch2\u003eLivagen (Lys-Glu-Ala-Ser) — Hepatic Bioregulator Peptide for Liver Research\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eLivagen\u003c\/strong\u003e is a synthetic tetrapeptide bioregulator (Lys-Glu-Ala-Ser) developed at the St. Petersburg Institute of Bioregulation and Gerontology by Professor Vladimir Khavinson. This liver-specific bioregulator has been extensively characterized for its capacity to modulate hepatocyte gene expression, restore liver detoxification enzyme activity, and normalize hepatic regenerative capacity in aged and chemically challenged liver tissue models. Published research in \u003cem\u003eBulletin of Experimental Biology and Medicine\u003c\/em\u003e has documented its unique mechanism of chromatin decondensation in hepatocyte nuclei.\u003c\/p\u003e\n\n\u003ch3\u003eMechanism of Action\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eLivagen\u003c\/strong\u003e represents one of the most thoroughly studied Khavinson bioregulators at the molecular level. The KEAS tetrapeptide has been demonstrated to induce decondensation of heterochromatin in hepatocyte nuclei, reactivating previously silenced gene regions. Specifically, research using atomic force microscopy and FISH analysis has shown that Livagen promotes unfolding of pericentromeric satellite DNA regions, increasing transcriptional accessibility at loci encoding cytochrome P450 enzymes (CYP1A2, CYP3A4), glutathione S-transferase isoforms, and albumin synthesis machinery.\u003c\/p\u003e\n\n\u003ch3\u003eKey Research Areas\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eChromatin Remodeling:\u003c\/strong\u003e Landmark studies have demonstrated that \u003cstrong\u003eLivagen\u003c\/strong\u003e induces measurable chromatin decondensation in hepatocyte nuclei within hours of treatment, increasing the proportion of transcriptionally active euchromatin—a finding confirmed by both DAPI staining and DNase I hypersensitivity assays.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHepatic Detoxification:\u003c\/strong\u003e Research has shown normalization of cytochrome P450 enzyme activity profiles in aged hepatocyte cultures, with significant restoration of CYP1A2 and CYP3A4 catalytic capacity following Livagen treatment.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLiver Regeneration:\u003c\/strong\u003e Partial hepatectomy models have demonstrated enhanced regenerative response in Livagen-pretreated animals, with increased hepatocyte proliferation rates (Ki-67 positivity) and preserved lobular architecture during regrowth.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHepatoprotection:\u003c\/strong\u003e Studies in CCl₄-induced liver injury models have shown reduced transaminase elevation, decreased oxidative stress markers (MDA, 4-HNE), and preserved glutathione reserves following Livagen administration.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003eTechnical Specifications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eDosage per vial:\u003c\/strong\u003e 10mg lyophilized powder\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity:\u003c\/strong\u003e ≥98% (HPLC verified)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSequence:\u003c\/strong\u003e Lys-Glu-Ala-Ser (KEAS tetrapeptide)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Weight:\u003c\/strong\u003e 433.46 Da\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStorage:\u003c\/strong\u003e -20°C, protected from light\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003eWhy Researchers Choose Peptides BioLab\u003c\/h3\u003e\n\u003cp\u003eEvery batch of \u003cstrong\u003eLivagen\u003c\/strong\u003e supplied by Peptides BioLab undergoes rigorous HPLC and mass spectrometry analysis, ensuring ≥98% purity verified by an independent Certificate of Analysis (CoA). Our product is supplied as a lyophilized powder for maximum stability, shipped worldwide in temperature-controlled packaging.\u003c\/p\u003e\n\n\u003ch3\u003eRelated Research Peptides\u003c\/h3\u003e\n\u003cp\u003eResearchers studying hepatic bioregulation and liver biology may also find these compounds relevant: \u003ca href=\"\/products\/bpc-157\"\u003eBPC-157\u003c\/a\u003e, \u003ca href=\"\/products\/thymalin\"\u003eThymalin\u003c\/a\u003e, and \u003ca href=\"\/products\/nad\"\u003eNAD+\u003c\/a\u003e. For a complete overview, browse our \u003ca href=\"\/collections\/recovery\"\u003eRecovery Research\u003c\/a\u003e collection.\u003c\/p\u003e\n\n\u003cp\u003e\u003cem\u003eFor research purposes only — Not for human consumption. All products are intended solely for in-vitro research and laboratory use.\u003c\/em\u003e\u003c\/p\u003e\n\u003c\/div\u003e","brand":"Peptides BioLab","offers":[{"title":"Default Title","offer_id":61420761186634,"sku":"PBL-LIVAGEN-10MG","price":29.99,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0998\/9429\/6906\/files\/peptides-biolab-livagen-bioregulator-peptide-10mg-research-grade.webp?v=1774393581"},{"product_id":"cartalax","title":"Cartalax","description":"\u003cdiv class=\"pb-product-desc\"\u003e\n\u003ch2\u003eCartalax (Ala-Glu-Asp) — Cartilage Bioregulator Peptide for Musculoskeletal Research\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eCartalax\u003c\/strong\u003e is a synthetic tripeptide bioregulator (Ala-Glu-Asp) developed at the St. Petersburg Institute of Bioregulation and Gerontology under the direction of Professor Vladimir Khavinson. While sharing the AED sequence with Bronchogen, Cartalax has been specifically characterized and optimized for its regulatory effects on cartilage tissue homeostasis and chondrocyte function. Published research has demonstrated its capacity to modulate extracellular matrix synthesis, normalize chondrocyte metabolism, and promote cartilage tissue resilience in both aged and mechanically stressed experimental models.\u003c\/p\u003e\n\n\u003ch3\u003eMechanism of Action\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eCartalax\u003c\/strong\u003e interacts with DNA sequences in promoter regions of genes critical for cartilage extracellular matrix maintenance. The tripeptide modulates transcription of type II collagen (COL2A1), aggrecan (ACAN), and cartilage oligomeric matrix protein (COMP) through chromatin remodeling at chondrocyte-specific gene loci. Research has also demonstrated Cartalax-mediated upregulation of SOX9—the master transcription factor for chondrocyte phenotype maintenance—while reducing expression of catabolic enzymes including MMP-13 and ADAMTS-5 that drive cartilage matrix degradation.\u003c\/p\u003e\n\n\u003ch3\u003eKey Research Areas\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eChondrocyte Metabolism:\u003c\/strong\u003e In-vitro studies on primary human articular chondrocytes have demonstrated that \u003cstrong\u003eCartalax\u003c\/strong\u003e increases glycosaminoglycan (GAG) synthesis rates and type II collagen deposition in three-dimensional pellet culture systems, with effects measurable by Alcian blue staining and hydroxyproline assays.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMatrix Protection:\u003c\/strong\u003e Research has shown that Cartalax reduces IL-1β-stimulated MMP-13 expression and aggrecan degradation fragment generation in cartilage explant cultures, suggesting anti-catabolic properties relevant to osteoarthritis research.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStem Cell Chondrogenesis:\u003c\/strong\u003e Studies on mesenchymal stem cell differentiation have observed enhanced chondrogenic commitment when Cartalax is included in differentiation media, with increased SOX9 and COL2A1 expression compared to standard protocols.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAge-Related Cartilage Changes:\u003c\/strong\u003e Histological analysis of articular cartilage from aged Cartalax-treated animals has shown preserved Safranin-O staining intensity, maintained cartilage thickness, and reduced surface fibrillation scores compared to untreated controls.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003eTechnical Specifications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eDosage per vial:\u003c\/strong\u003e 10mg lyophilized powder\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity:\u003c\/strong\u003e ≥98% (HPLC verified)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSequence:\u003c\/strong\u003e Ala-Glu-Asp (AED tripeptide)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Weight:\u003c\/strong\u003e 333.29 Da\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStorage:\u003c\/strong\u003e -20°C, protected from light\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003eWhy Researchers Choose Peptides BioLab\u003c\/h3\u003e\n\u003cp\u003eEvery batch of \u003cstrong\u003eCartalax\u003c\/strong\u003e supplied by Peptides BioLab undergoes rigorous HPLC and mass spectrometry analysis, ensuring ≥98% purity verified by an independent Certificate of Analysis (CoA). Our product is supplied as a lyophilized powder for maximum stability, shipped worldwide in temperature-controlled packaging.\u003c\/p\u003e\n\n\u003ch3\u003eRelated Research Peptides\u003c\/h3\u003e\n\u003cp\u003eResearchers studying cartilage biology and musculoskeletal repair may also find these compounds relevant: \u003ca href=\"\/products\/bpc-157\"\u003eBPC-157\u003c\/a\u003e, \u003ca href=\"\/products\/tb-500\"\u003eTB-500\u003c\/a\u003e, and \u003ca href=\"\/products\/ghk-cu\"\u003eGHK-Cu\u003c\/a\u003e. For a complete overview, browse our \u003ca href=\"\/collections\/recovery\"\u003eRecovery Research\u003c\/a\u003e collection.\u003c\/p\u003e\n\n\u003cp\u003e\u003cem\u003eFor research purposes only — Not for human consumption. All products are intended solely for in-vitro research and laboratory use.\u003c\/em\u003e\u003c\/p\u003e\n\u003c\/div\u003e","brand":"Peptides BioLab","offers":[{"title":"Default Title","offer_id":61420761776458,"sku":"PBL-CARTALAX-10MG","price":29.99,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0998\/9429\/6906\/files\/peptides-biolab-cartalax-bioregulator-peptide-10mg-research-grade.webp?v=1774393586"},{"product_id":"chonluten","title":"Chonluten","description":"\u003cdiv class=\"pb-product-desc\"\u003e\n\u003ch2\u003eChonluten (Glu-Asp-Gly) — Pulmonary\/Gastrointestinal Bioregulator for Mucosal Tissue Research\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eChonluten\u003c\/strong\u003e is a synthetic tripeptide bioregulator (Glu-Asp-Gly) developed at the St. Petersburg Institute of Bioregulation and Gerontology by Professor Vladimir Khavinson. This short bioregulator peptide has been characterized for its dual tissue specificity, demonstrating regulatory effects on both bronchial mucosal and gastrointestinal epithelial tissue gene expression. Published research in \u003cem\u003eBulletin of Experimental Biology and Medicine\u003c\/em\u003e has documented its ability to normalize mucosal barrier function, restore epithelial turnover kinetics, and modulate local immune responses in both respiratory and digestive tract tissue models.\u003c\/p\u003e\n\n\u003ch3\u003eMechanism of Action\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eChonluten\u003c\/strong\u003e interacts with DNA sequences in promoter regions of genes governing mucosal epithelial integrity across multiple organ systems. The EDG tripeptide modulates transcription of tight junction proteins (ZO-1, claudins), mucin genes (MUC2, MUC5AC), and defensin antimicrobial peptides through chromatin remodeling at tissue-specific loci. Research has demonstrated that Chonluten simultaneously upregulates epithelial repair mechanisms while modulating the innate immune response at mucosal surfaces, maintaining the delicate balance between barrier defense and inflammatory control.\u003c\/p\u003e\n\n\u003ch3\u003eKey Research Areas\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eMucosal Barrier Function:\u003c\/strong\u003e Trans-epithelial electrical resistance (TEER) measurements have demonstrated that \u003cstrong\u003eChonluten\u003c\/strong\u003e enhances barrier integrity in both Caco-2 intestinal monolayers and primary bronchial epithelial cell cultures, with significant upregulation of tight junction protein expression.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEpithelial Regeneration:\u003c\/strong\u003e Wound healing assays on mucosal epithelial cell monolayers have shown accelerated gap closure and enhanced proliferative response following Chonluten treatment, with increased Ki-67 positivity and reduced apoptotic indices in the wound margin.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMucosal Immunity:\u003c\/strong\u003e Research has observed modulation of secretory IgA production and defensin expression at mucosal surfaces, suggesting that Chonluten supports local antimicrobial defense while preventing excessive inflammatory activation.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAge-Related Mucosal Changes:\u003c\/strong\u003e Histological studies in aged animal gastrointestinal tissue have documented preserved villus height, maintained crypt depth ratio, and normalized goblet cell density following chronic Chonluten administration.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003eTechnical Specifications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eDosage per vial:\u003c\/strong\u003e 10mg lyophilized powder\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity:\u003c\/strong\u003e ≥98% (HPLC verified)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSequence:\u003c\/strong\u003e Glu-Asp-Gly (EDG tripeptide)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Weight:\u003c\/strong\u003e 319.27 Da\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStorage:\u003c\/strong\u003e -20°C, protected from light\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003eWhy Researchers Choose Peptides BioLab\u003c\/h3\u003e\n\u003cp\u003eEvery batch of \u003cstrong\u003eChonluten\u003c\/strong\u003e supplied by Peptides BioLab undergoes rigorous HPLC and mass spectrometry analysis, ensuring ≥98% purity verified by an independent Certificate of Analysis (CoA). Our product is supplied as a lyophilized powder for maximum stability, shipped worldwide in temperature-controlled packaging.\u003c\/p\u003e\n\n\u003ch3\u003eRelated Research Peptides\u003c\/h3\u003e\n\u003cp\u003eResearchers studying mucosal bioregulation may also find these compounds relevant: \u003ca href=\"\/products\/bpc-157\"\u003eBPC-157\u003c\/a\u003e, \u003ca href=\"\/products\/kpv\"\u003eKPV\u003c\/a\u003e, and \u003ca href=\"\/products\/ll-37\"\u003eLL-37\u003c\/a\u003e. For a complete overview, browse our \u003ca href=\"\/collections\/recovery\"\u003eRecovery Research\u003c\/a\u003e collection.\u003c\/p\u003e\n\n\u003cp\u003e\u003cem\u003eFor research purposes only — Not for human consumption. All products are intended solely for in-vitro research and laboratory use.\u003c\/em\u003e\u003c\/p\u003e\n\u003c\/div\u003e","brand":"Peptides BioLab","offers":[{"title":"Default Title","offer_id":61420761940298,"sku":"PBL-CHONLUTEN-10MG","price":29.99,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0998\/9429\/6906\/files\/peptides-biolab-chonluten-bioregulator-peptide-10mg-research-grade.webp?v=1774393588"},{"product_id":"crystagen","title":"Crystagen","description":"\u003cdiv class=\"pb-product-desc\"\u003e\n\u003ch2\u003eCrystagen (Glu-Asp-Pro) — Immune System Bioregulator for Immunological Research\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eCrystagen\u003c\/strong\u003e is a synthetic tripeptide bioregulator (Glu-Asp-Pro) developed at the St. Petersburg Institute of Bioregulation and Gerontology under the direction of Professor Vladimir Khavinson. This immune-specific bioregulator has been characterized for its regulatory effects on immunocompetent cell function, particularly lymphocyte differentiation, cytokine network balance, and innate immune surveillance capacity. Published research in \u003cem\u003eBulletin of Experimental Biology and Medicine\u003c\/em\u003e has documented its ability to restore age-diminished immune parameters and normalize immune homeostasis in both in-vitro and in-vivo experimental systems.\u003c\/p\u003e\n\n\u003ch3\u003eMechanism of Action\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eCrystagen\u003c\/strong\u003e modulates gene expression in immunocompetent cells through the characteristic Khavinson bioregulator mechanism of direct DNA interaction. The EDP tripeptide binds specific nucleotide sequences in promoter regions of genes governing immune cell activation, differentiation, and effector function. Research has demonstrated modulation of cytokine gene expression profiles (IL-2, IFN-γ, IL-4, IL-10), normalization of T-helper 1\/T-helper 2 balance, and upregulation of pattern recognition receptor (TLR) expression on innate immune cells, collectively enhancing immune surveillance without promoting excessive inflammatory activation.\u003c\/p\u003e\n\n\u003ch3\u003eKey Research Areas\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eLymphocyte Function:\u003c\/strong\u003e In-vitro studies on peripheral blood mononuclear cells (PBMCs) have demonstrated that \u003cstrong\u003eCrystagen\u003c\/strong\u003e enhances mitogen-stimulated lymphocyte proliferation, increases CD3+ T-cell activation markers (CD25, CD69), and restores age-diminished cytokine production capacity.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eInnate Immunity:\u003c\/strong\u003e Research has shown that Crystagen upregulates phagocytic activity of monocytes and neutrophils, enhances natural killer cell cytotoxicity against K562 target cells, and increases reactive oxygen species generation capacity in professional phagocytes.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eImmunosenescence Reversal:\u003c\/strong\u003e Studies in aged rodent models have documented restoration of splenic T-cell zone architecture, normalization of naive\/memory T-cell ratios, and enhanced response to vaccination protocols following Crystagen treatment.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCytokine Network Balance:\u003c\/strong\u003e Multiplex cytokine analysis has revealed that Crystagen normalizes the Th1\/Th2\/Th17\/Treg balance in aged immune systems, reducing excessive inflammatory cytokine production while preserving protective immune responses.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003eTechnical Specifications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eDosage per vial:\u003c\/strong\u003e 10mg lyophilized powder\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity:\u003c\/strong\u003e ≥98% (HPLC verified)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSequence:\u003c\/strong\u003e Glu-Asp-Pro (EDP tripeptide)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Weight:\u003c\/strong\u003e 359.33 Da\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStorage:\u003c\/strong\u003e -20°C, protected from light\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003eWhy Researchers Choose Peptides BioLab\u003c\/h3\u003e\n\u003cp\u003eEvery batch of \u003cstrong\u003eCrystagen\u003c\/strong\u003e supplied by Peptides BioLab undergoes rigorous HPLC and mass spectrometry analysis, ensuring ≥98% purity verified by an independent Certificate of Analysis (CoA). Our product is supplied as a lyophilized powder for maximum stability, shipped worldwide in temperature-controlled packaging.\u003c\/p\u003e\n\n\u003ch3\u003eRelated Research Peptides\u003c\/h3\u003e\n\u003cp\u003eResearchers studying immune bioregulation may also find these compounds relevant: \u003ca href=\"\/products\/vilon\"\u003eVilon\u003c\/a\u003e, \u003ca href=\"\/products\/thymalin\"\u003eThymalin\u003c\/a\u003e, and \u003ca href=\"\/products\/thymosin-alpha-1\"\u003eThymosin Alpha-1\u003c\/a\u003e. For a complete overview, browse our \u003ca href=\"\/collections\/recovery\"\u003eRecovery Research\u003c\/a\u003e collection.\u003c\/p\u003e\n\n\u003cp\u003e\u003cem\u003eFor research purposes only — Not for human consumption. All products are intended solely for in-vitro research and laboratory use.\u003c\/em\u003e\u003c\/p\u003e\n\u003c\/div\u003e","brand":"Peptides BioLab","offers":[{"title":"Default Title","offer_id":61420762071370,"sku":"PBL-CRYSTAGEN-10MG","price":29.99,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0998\/9429\/6906\/files\/peptides-biolab-crystagen-bioregulator-peptide-10mg-research-grade.webp?v=1774393590"},{"product_id":"ovagen","title":"Ovagen","description":"\u003cdiv class=\"pb-product-desc\"\u003e\n\u003ch2\u003eOvagen (Glu-Asp-Leu) — Hepato-Gastrointestinal Bioregulator for Digestive Research\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eOvagen\u003c\/strong\u003e is a synthetic tripeptide bioregulator (Glu-Asp-Leu) developed at the St. Petersburg Institute of Bioregulation and Gerontology by Professor Vladimir Khavinson. Originally derived from research on hepatic and gastrointestinal tissue extracts, Ovagen has been characterized for its dual regulatory effects on liver function and gastrointestinal epithelial homeostasis. Published research in \u003cem\u003eBulletin of Experimental Biology and Medicine\u003c\/em\u003e has documented its capacity to normalize digestive enzyme secretion, restore hepatobiliary function, and support mucosal integrity across the gastrointestinal tract in aged experimental models.\u003c\/p\u003e\n\n\u003ch3\u003eMechanism of Action\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eOvagen\u003c\/strong\u003e interacts with DNA sequences in promoter regions of genes governing both hepatocyte function and gastrointestinal epithelial differentiation. The EDL tripeptide modulates transcription of key digestive enzymes, bile acid transport proteins (BSEP, MRP2), and intestinal epithelial differentiation markers through chromatin remodeling. Research has demonstrated simultaneous normalization of hepatic phase I\/II detoxification enzyme expression and intestinal brush border enzyme activity (alkaline phosphatase, sucrase-isomaltase), suggesting a coordinated regulatory effect across the digestive axis.\u003c\/p\u003e\n\n\u003ch3\u003eKey Research Areas\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eHepatobiliary Function:\u003c\/strong\u003e In-vitro studies on primary hepatocyte cultures have demonstrated that \u003cstrong\u003eOvagen\u003c\/strong\u003e normalizes bile acid synthesis enzyme expression (CYP7A1, CYP27A1) and enhances canalicular transport protein activity, improving bile flow parameters in perfused liver preparations.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGastrointestinal Epithelial Renewal:\u003c\/strong\u003e Research on intestinal organoid cultures has shown enhanced crypt cell proliferation and accelerated differentiation into absorptive enterocytes and goblet cells following Ovagen treatment, with preserved stem cell niche integrity.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDigestive Enzyme Regulation:\u003c\/strong\u003e Studies have documented normalized pancreatic exocrine enzyme secretion (amylase, lipase, trypsin) and gastric acid output in aged animal models, restoring digestive efficiency to levels approaching younger controls.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGut-Liver Axis:\u003c\/strong\u003e Research has explored Ovagen's effects on the gut-liver axis, documenting improved intestinal barrier function (reduced plasma endotoxin levels) concurrent with enhanced hepatic clearance capacity in aged animal models.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003eTechnical Specifications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eDosage per vial:\u003c\/strong\u003e 10mg lyophilized powder\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity:\u003c\/strong\u003e ≥98% (HPLC verified)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSequence:\u003c\/strong\u003e Glu-Asp-Leu (EDL tripeptide)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Weight:\u003c\/strong\u003e 375.37 Da\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStorage:\u003c\/strong\u003e -20°C, protected from light\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003eWhy Researchers Choose Peptides BioLab\u003c\/h3\u003e\n\u003cp\u003eEvery batch of \u003cstrong\u003eOvagen\u003c\/strong\u003e supplied by Peptides BioLab undergoes rigorous HPLC and mass spectrometry analysis, ensuring ≥98% purity verified by an independent Certificate of Analysis (CoA). Our product is supplied as a lyophilized powder for maximum stability, shipped worldwide in temperature-controlled packaging.\u003c\/p\u003e\n\n\u003ch3\u003eRelated Research Peptides\u003c\/h3\u003e\n\u003cp\u003eResearchers studying digestive bioregulation may also find these compounds relevant: \u003ca href=\"\/products\/livagen\"\u003eLivagen\u003c\/a\u003e, \u003ca href=\"\/products\/bpc-157\"\u003eBPC-157\u003c\/a\u003e, and \u003ca href=\"\/products\/kpv\"\u003eKPV\u003c\/a\u003e. For a complete overview, browse our \u003ca href=\"\/collections\/recovery\"\u003eRecovery Research\u003c\/a\u003e collection.\u003c\/p\u003e\n\n\u003cp\u003e\u003cem\u003eFor research purposes only — Not for human consumption. All products are intended solely for in-vitro research and laboratory use.\u003c\/em\u003e\u003c\/p\u003e\n\u003c\/div\u003e","brand":"Peptides BioLab","offers":[{"title":"Default Title","offer_id":61420762267978,"sku":"PBL-OVAGEN-10MG","price":29.99,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0998\/9429\/6906\/files\/peptides-biolab-ovagen-bioregulator-peptide-10mg-research-grade.webp?v=1774393591"},{"product_id":"vesugen","title":"Vesugen","description":"\u003cdiv class=\"pb-product-desc\"\u003e\n\u003ch2\u003eVesugen (Lys-Glu-Asp) — Vascular Bioregulator Peptide for Cardiovascular Research\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eVesugen\u003c\/strong\u003e is a synthetic tripeptide bioregulator (Lys-Glu-Asp) developed at the St. Petersburg Institute of Bioregulation and Gerontology under the direction of Professor Vladimir Khavinson. As a vascular-specific bioregulator, Vesugen has been characterized for its regulatory effects on endothelial cell gene expression, vascular tone maintenance, and blood vessel wall integrity. Published research in \u003cem\u003eBulletin of Experimental Biology and Medicine\u003c\/em\u003e and \u003cem\u003eAdvances in Gerontology\u003c\/em\u003e has documented its capacity to normalize endothelial function, restore nitric oxide signaling, and preserve vascular architecture in aged experimental models.\u003c\/p\u003e\n\n\u003ch3\u003eMechanism of Action\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eVesugen\u003c\/strong\u003e interacts with DNA sequences in promoter regions of genes critical for endothelial cell function and vascular homeostasis. The KED tripeptide modulates transcription of endothelial nitric oxide synthase (eNOS), prostacyclin synthase (PGIS), and vascular endothelial growth factor receptors through chromatin remodeling at endothelial-specific gene loci. Research has demonstrated that Vesugen restores age-diminished eNOS expression and enzymatic activity, improving endothelium-dependent vasodilation capacity while simultaneously downregulating pro-thrombotic endothelin-1 (ET-1) expression.\u003c\/p\u003e\n\n\u003ch3\u003eKey Research Areas\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eEndothelial Function:\u003c\/strong\u003e In-vitro studies on human umbilical vein endothelial cells (HUVECs) have demonstrated that \u003cstrong\u003eVesugen\u003c\/strong\u003e enhances NO production, reduces endothelial activation markers (VCAM-1, ICAM-1, E-selectin), and preserves endothelial barrier function under inflammatory stress conditions.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eVascular Aging:\u003c\/strong\u003e Research in aged murine models has shown improved flow-mediated dilation, restored aortic compliance, and reduced arterial wall thickening following chronic Vesugen administration, with effects correlated to normalized eNOS\/ET-1 expression ratios.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAnti-Atherogenic Effects:\u003c\/strong\u003e Studies have documented reduced monocyte adhesion to Vesugen-treated endothelial monolayers, decreased foam cell formation, and attenuated intimal thickening in hyperlipidemic animal models.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMicrocirculation:\u003c\/strong\u003e Intravital microscopy studies have observed improved capillary perfusion patterns, normalized leukocyte rolling velocity, and reduced microvascular permeability in aged tissues following Vesugen treatment.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003eTechnical Specifications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eDosage per vial:\u003c\/strong\u003e 10mg lyophilized powder\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity:\u003c\/strong\u003e ≥98% (HPLC verified)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSequence:\u003c\/strong\u003e Lys-Glu-Asp (KED tripeptide)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular Weight:\u003c\/strong\u003e 390.39 Da\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStorage:\u003c\/strong\u003e -20°C, protected from light\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003eWhy Researchers Choose Peptides BioLab\u003c\/h3\u003e\n\u003cp\u003eEvery batch of \u003cstrong\u003eVesugen\u003c\/strong\u003e supplied by Peptides BioLab undergoes rigorous HPLC and mass spectrometry analysis, ensuring ≥98% purity verified by an independent Certificate of Analysis (CoA). Our product is supplied as a lyophilized powder for maximum stability, shipped worldwide in temperature-controlled packaging.\u003c\/p\u003e\n\n\u003ch3\u003eRelated Research Peptides\u003c\/h3\u003e\n\u003cp\u003eResearchers studying vascular bioregulation may also find these compounds relevant: \u003ca href=\"\/products\/cardiogen\"\u003eCardiogen\u003c\/a\u003e, \u003ca href=\"\/products\/bpc-157\"\u003eBPC-157\u003c\/a\u003e, and \u003ca href=\"\/products\/ghk-cu\"\u003eGHK-Cu\u003c\/a\u003e. For a complete overview, browse our \u003ca href=\"\/collections\/recovery\"\u003eRecovery Research\u003c\/a\u003e collection.\u003c\/p\u003e\n\n\u003cp\u003e\u003cem\u003eFor research purposes only — Not for human consumption. All products are intended solely for in-vitro research and laboratory use.\u003c\/em\u003e\u003c\/p\u003e\n\u003c\/div\u003e","brand":"Peptides BioLab","offers":[{"title":"Default Title","offer_id":61420762497354,"sku":"PBL-VESUGEN-10MG","price":29.99,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0998\/9429\/6906\/files\/peptides-biolab-vesugen-bioregulator-peptide-10mg-research-grade.webp?v=1774393593"}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0998\/9429\/6906\/collections\/peptides-biolab-tb-500-thymosin-beta-4-peptide-10mg-research-grade.webp?v=1774382739","url":"https:\/\/peptides-biolab.com\/collections\/recovery.oembed","provider":"Peptides BioLab","version":"1.0","type":"link"}