{"product_id":"ahk-cu","title":"AHK-CU","description":"\u003cdiv class=\"pb-product-desc\"\u003e\n\u003ch2\u003eAHK-Cu — Copper Tripeptide Analog for Dermatological and Follicular Research\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eAHK-Cu\u003c\/strong\u003e (Ala-His-Lys-Cu) is a copper-binding tripeptide analog structurally related to GHK-Cu, designed to investigate dermatological regeneration and hair follicle biology. This peptide-copper complex has demonstrated affinity for copper(II) ions and activity in stimulating dermal papilla cell proliferation in published in-vitro research. As a next-generation copper peptide, \u003cstrong\u003eAHK-Cu\u003c\/strong\u003e offers researchers a distinct molecular tool for studying extracellular matrix remodeling and follicular signaling pathways.\u003c\/p\u003e\n\n\u003ch3\u003eMechanism of Action\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eAHK-Cu\u003c\/strong\u003e chelates copper(II) ions and delivers them to target cells, where copper serves as a cofactor for lysyl oxidase and other enzymes critical for collagen cross-linking and extracellular matrix assembly. Research published in the \u003cem\u003eJournal of Cosmetic Dermatology\u003c\/em\u003e has shown that AHK-Cu stimulates Wnt\/β-catenin signaling in dermal papilla cells, a pathway essential for hair follicle morphogenesis and cycling. Additionally, the peptide has been observed to upregulate VEGF expression, potentially enhancing perifollicular vascularization in tissue models.\u003c\/p\u003e\n\n\u003ch3\u003eKey Research Areas\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eHair Follicle Biology:\u003c\/strong\u003e In-vitro studies using human dermal papilla cells have demonstrated that \u003cstrong\u003eAHK-Cu\u003c\/strong\u003e promotes cell proliferation and upregulates growth factors associated with the anagen (growth) phase of the hair cycle, including FGF-7 and VEGF.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCollagen Synthesis:\u003c\/strong\u003e Copper peptide complexes including AHK-Cu have been investigated for their role in stimulating type I and type III collagen production in fibroblast cultures, with potential applications in wound healing and skin aging research.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eExtracellular Matrix Remodeling:\u003c\/strong\u003e Research has examined how copper delivery via AHK-Cu modulates matrix metalloproteinase (MMP) activity, balancing tissue degradation and synthesis in skin equivalent models.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eScalp Microenvironment:\u003c\/strong\u003e Studies have explored AHK-Cu's effects on the perifollicular microenvironment, including its influence on stem cell niche signaling and inflammatory cytokine modulation in scalp tissue models.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003eWhy Researchers Choose Peptides BioLab\u003c\/h3\u003e\n\u003cp\u003eEvery batch of \u003cstrong\u003eAHK-Cu\u003c\/strong\u003e supplied by Peptides BioLab undergoes rigorous HPLC and mass spectrometry analysis, ensuring ≥98% purity verified by an independent Certificate of Analysis (CoA). Our \u003ca href=\"\/products\/ahk-cu\"\u003eAHK-Cu\u003c\/a\u003e is supplied as a lyophilized powder for maximum stability and shelf life, shipped worldwide from our state-of-the-art facilities in temperature-controlled packaging.\u003c\/p\u003e\n\n\u003ch3\u003eRelated Research Peptides\u003c\/h3\u003e\n\u003cp\u003eResearchers studying copper peptide biology and dermatological pathways may also find these compounds relevant: \u003ca href=\"\/products\/ghk-cu\"\u003eGHK-Cu\u003c\/a\u003e, \u003ca href=\"\/products\/snap-8\"\u003eSNAP-8\u003c\/a\u003e, and \u003ca href=\"\/products\/melanotan-ii\"\u003eMelanotan II\u003c\/a\u003e. For a complete overview, browse our \u003ca href=\"\/collections\/anti-aging\"\u003eDermatological Research\u003c\/a\u003e collection.\u003c\/p\u003e\n\n\u003cp\u003e\u003cem\u003eFor research purposes only — Not for human consumption. All products are intended solely for in-vitro research and laboratory use.\u003c\/em\u003e\u003c\/p\u003e\n\u003c\/div\u003e","brand":"Peptides BioLab","offers":[{"title":"Default Title","offer_id":60995752657226,"sku":"PBL-AHK-CU-6G","price":59.99,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0998\/9429\/6906\/files\/peptides-biolab-ahk-cu-copper-tripeptide-50mg-research-grade.webp?v=1773935011","url":"https:\/\/peptides-biolab.com\/products\/ahk-cu","provider":"Peptides BioLab","version":"1.0","type":"link"}