{"product_id":"epithalon","title":"Epitalon","description":"\u003cdiv class=\"pb-product-desc\"\u003e\n\u003ch2\u003eEpitalon — Synthetic Tetrapeptide for Telomerase and Longevity Research\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eEpitalon\u003c\/strong\u003e (Ala-Glu-Asp-Gly) is a synthetic analog of pineal epithalamin developed by Professor Vladimir Khavinson. Published in \u003cem\u003eBulletin of Experimental Biology and Medicine\u003c\/em\u003e (2003): telomerase reactivation in human somatic cells.\u003c\/p\u003e\n\u003ch3\u003eMechanism of Action\u003c\/h3\u003e\n\u003cp\u003eEpitalon stimulates hTERT expression, the catalytic subunit of telomerase. Khavinson et al. demonstrated telomerase activation in human fetal fibroblasts extending proliferative capacity beyond the Hayflick limit. Also normalizes circadian melatonin secretion in aged models and modulates antioxidant enzymes (SOD, GPx).\u003c\/p\u003e\n\u003ch3\u003eKey Research Areas\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eTelomere Biology:\u003c\/strong\u003e One of few peptides shown to activate telomerase in human somatic cells, extending replicative lifespan with maintained genomic stability.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePineal Gland Function:\u003c\/strong\u003e Restores nighttime melatonin peak and normalizes disrupted circadian rhythms in aged rodent models.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOxidative Stress:\u003c\/strong\u003e Increases SOD, catalase, GPx expression and reduces lipid peroxidation in aged tissues.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eChromatin Remodeling:\u003c\/strong\u003e Short peptides interact with specific DNA sequences, influencing chromatin states and senescence-associated gene expression.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eWhy Researchers Choose Peptides BioLab\u003c\/h3\u003e\n\u003cp\u003eEvery batch of \u003cstrong\u003eEpitalon\u003c\/strong\u003e supplied by Peptides BioLab undergoes rigorous HPLC and mass spectrometry analysis, ensuring ≥98% purity verified by an independent Certificate of Analysis (CoA). Our \u003ca href=\"\/products\/epithalon\"\u003eEpitalon\u003c\/a\u003e is supplied as a lyophilized powder for maximum stability and shelf life, shipped worldwide from our state-of-the-art facilities in temperature-controlled packaging.\u003c\/p\u003e\n\u003ch3\u003eRelated Research Peptides\u003c\/h3\u003e\n\u003cp\u003eResearchers studying related pathways may also find these compounds relevant: \u003ca href=\"\/products\/pinealon\"\u003ePinealon\u003c\/a\u003e, \u003ca href=\"\/products\/nad\"\u003eNAD+\u003c\/a\u003e, and \u003ca href=\"\/products\/ss-31\"\u003eSS-31\u003c\/a\u003e. Browse our \u003ca href=\"\/collections\/anti-aging\"\u003eLongevity Research\u003c\/a\u003e collection.\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eFor research purposes only — Not for human consumption. All products are intended solely for in-vitro research and laboratory use.\u003c\/em\u003e\u003c\/p\u003e\n\u003c\/div\u003e","brand":"Peptides BioLab","offers":[{"title":"10","offer_id":60995753410890,"sku":"PBL-EPITALON-10MG","price":34.99,"currency_code":"EUR","in_stock":true},{"title":"50","offer_id":60995753443658,"sku":"PBL-EPITALON-10MG","price":154.99,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0998\/9429\/6906\/files\/peptides-biolab-epitalon-telomerase-activator-peptide-10mg-research-grade.webp?v=1773935031","url":"https:\/\/peptides-biolab.com\/products\/epithalon","provider":"Peptides BioLab","version":"1.0","type":"link"}