{"product_id":"melanotan-ii","title":"Melanotan II","description":"\u003cdiv class=\"pb-product-desc\"\u003e\n\u003ch2\u003eMelanotan II — Cyclic Melanocortin Receptor Agonist for Pigmentation Research\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eMelanotan II\u003c\/strong\u003e (MT-II) is a synthetic cyclic heptapeptide α-MSH analog designed by Hruby \u0026amp; Hadley at University of Arizona. Non-selective melanocortin receptor agonist (MC1R, MC3R, MC4R, MC5R) for pigmentation, energy homeostasis, and behavioral research.\u003c\/p\u003e\n\u003ch3\u003eMechanism of Action\u003c\/h3\u003e\n\u003cp\u003eMT-II activates melanocortin receptors via Gs-cAMP signaling. At MC1R: cAMP-PKA-MITF-tyrosinase cascade for eumelanin synthesis. At MC4R: anorexigenic pathways and sexual arousal circuits. Induces melanogenesis independent of UV (\u003cem\u003ePeptides\u003c\/em\u003e, 1996). MC4R effects led to bremelanotide (PT-141) development.\u003c\/p\u003e\n\u003ch3\u003eKey Research Areas\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eMelanogenesis Research:\u003c\/strong\u003e Stimulates melanin production via MC1R-cAMP-MITF pathway for UV-independent pigmentation studies.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMC Receptor Pharmacology:\u003c\/strong\u003e Non-selective reference compound for studying melanocortin receptor subtypes and developing selective analogs.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEnergy Homeostasis:\u003c\/strong\u003e MC3R\/MC4R activation modulates hypothalamic feeding circuits and leptin-melanocortin pathway interactions.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePhotoprotection:\u003c\/strong\u003e Investigating melanocortin-stimulated melanogenesis for protective effects against UV-induced DNA damage.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eWhy Researchers Choose Peptides BioLab\u003c\/h3\u003e\n\u003cp\u003eEvery batch of \u003cstrong\u003eMelanotan II\u003c\/strong\u003e supplied by Peptides BioLab undergoes rigorous HPLC and mass spectrometry analysis, ensuring ≥98% purity verified by an independent Certificate of Analysis (CoA). Our \u003ca href=\"\/products\/melanotan-ii\"\u003eMelanotan II\u003c\/a\u003e is supplied as a lyophilized powder for maximum stability and shelf life, shipped worldwide from our state-of-the-art facilities in temperature-controlled packaging.\u003c\/p\u003e\n\u003ch3\u003eRelated Research Peptides\u003c\/h3\u003e\n\u003cp\u003eResearchers studying related pathways may also find these compounds relevant: \u003ca href=\"\/products\/pt-141\"\u003ePT-141\u003c\/a\u003e, \u003ca href=\"\/products\/snap-8\"\u003eSNAP-8\u003c\/a\u003e, and \u003ca href=\"\/products\/ahk-cu\"\u003eAHK-Cu\u003c\/a\u003e. Browse our \u003ca href=\"\/collections\/anti-aging\"\u003eDermatological Research\u003c\/a\u003e collection.\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eFor research purposes only — Not for human consumption. All products are intended solely for in-vitro research and laboratory use.\u003c\/em\u003e\u003c\/p\u003e\n\u003c\/div\u003e","brand":"Peptides BioLab","offers":[{"title":"Default Title","offer_id":60995753607498,"sku":"PBL-MELANOTANII-10MG","price":39.99,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0998\/9429\/6906\/files\/peptides-biolab-melanotan-ii-peptide-10mg-research-grade.webp?v=1773933887","url":"https:\/\/peptides-biolab.com\/products\/melanotan-ii","provider":"Peptides BioLab","version":"1.0","type":"link"}