{"product_id":"selank","title":"Selank","description":"\u003cdiv class=\"pb-product-desc\"\u003e\n\u003ch2\u003eSelank — Tuftsin-Derived Heptapeptide for Anxiolytic and Cognitive Research\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eSelank\u003c\/strong\u003e (Thr-Lys-Pro-Arg-Pro-Gly-Pro) is a synthetic tuftsin analog with Pro-Gly-Pro extension for stability. Developed at the Institute of Molecular Genetics, Russian Academy of Sciences. Combined anxiolytic and nootropic properties without sedation or dependence.\u003c\/p\u003e\n\u003ch3\u003eMechanism of Action\u003c\/h3\u003e\n\u003cp\u003eSelank allosterically enhances GABA-A receptor sensitivity without direct benzodiazepine-site binding. Increases hippocampal BDNF mRNA. Stabilizes enkephalin levels by inhibiting enkephalinase. Modulates 36 genes related to GABAergic, serotonergic, and dopaminergic neurotransmission in the hippocampus.\u003c\/p\u003e\n\u003ch3\u003eKey Research Areas\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eGABAergic Modulation:\u003c\/strong\u003e Allosteric GABA-A enhancement providing anxiolytic effects without sedation, tolerance, or withdrawal.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBDNF and Neuroplasticity:\u003c\/strong\u003e Increased hippocampal BDNF with downstream TrkB-CREB signaling for LTP and memory consolidation.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEnkephalin Metabolism:\u003c\/strong\u003e Inhibits enkephalin-degrading enzymes for elevated endogenous opioid signaling without mu-agonism.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eImmune-Neuro Crosstalk:\u003c\/strong\u003e Retains tuftsin immunomodulatory properties (phagocytosis, IL-6) for studying nervous-immune bidirectional communication.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eWhy Researchers Choose Peptides BioLab\u003c\/h3\u003e\n\u003cp\u003eEvery batch of \u003cstrong\u003eSelank\u003c\/strong\u003e supplied by Peptides BioLab undergoes rigorous HPLC and mass spectrometry analysis, ensuring ≥98% purity verified by an independent Certificate of Analysis (CoA). Our \u003ca href=\"\/products\/selank\"\u003eSelank\u003c\/a\u003e is supplied as a lyophilized powder for maximum stability and shelf life, shipped worldwide from our state-of-the-art facilities in temperature-controlled packaging.\u003c\/p\u003e\n\u003ch3\u003eRelated Research Peptides\u003c\/h3\u003e\n\u003cp\u003eResearchers studying related pathways may also find these compounds relevant: \u003ca href=\"\/products\/semax\"\u003eSemax\u003c\/a\u003e, \u003ca href=\"\/products\/pp-22-28\"\u003ePE-22-28\u003c\/a\u003e, and \u003ca href=\"\/products\/dsip\"\u003eDSIP\u003c\/a\u003e. Browse our \u003ca href=\"\/collections\/cognitive-function\"\u003eNootropic \u0026amp; Cognitive Research\u003c\/a\u003e collection.\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eFor research purposes only — Not for human consumption. All products are intended solely for in-vitro research and laboratory use.\u003c\/em\u003e\u003c\/p\u003e\n\u003c\/div\u003e","brand":"Peptides BioLab","offers":[{"title":"10","offer_id":60995753181514,"sku":"PBL-SELANK-6G","price":29.99,"currency_code":"EUR","in_stock":true},{"title":"30","offer_id":60995753214282,"sku":"PBL-SELANK-6G","price":79.99,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0998\/9429\/6906\/files\/peptides-biolab-selank-anxiolytic-nootropic-peptide-10mg-research-grade.webp?v=1773935024","url":"https:\/\/peptides-biolab.com\/products\/selank","provider":"Peptides BioLab","version":"1.0","type":"link"}