{"product_id":"semax","title":"Semax","description":"\u003cdiv class=\"pb-product-desc\"\u003e\n\u003ch2\u003eSemax — ACTH(4-10) Analog for Neurotrophic Factor and Cognitive Research\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eSemax\u003c\/strong\u003e (Met-Glu-His-Phe-Pro-Gly-Pro) is a synthetic ACTH(4-10) analog developed at the Institute of Molecular Genetics, Russian Academy of Sciences. Pro-Gly-Pro extension confers protease resistance without steroidogenic effects. Over 200 published studies on neurotrophic factor expression and cognitive performance.\u003c\/p\u003e\n\u003ch3\u003eMechanism of Action\u003c\/h3\u003e\n\u003cp\u003eSemax upregulates BDNF and TrkB in hippocampus and cortex, increases NGF expression, enhances 5-HT turnover, and activates the MAPK\/ERK cascade for neuronal survival under ischemic conditions.\u003c\/p\u003e\n\u003ch3\u003eKey Research Areas\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eBDNF \u0026amp; NGF Upregulation:\u003c\/strong\u003e Sustained increases in hippocampal BDNF and cortical NGF — enhanced neurotrophic support documented across independent research groups.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCognitive Enhancement Models:\u003c\/strong\u003e Improved Morris water maze, passive avoidance, and novel object recognition correlating with increased LTP.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNeuroprotection:\u003c\/strong\u003e Reduces infarct volume, preserves BBB integrity, maintains neuronal viability in stroke models.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGene Expression Profiling:\u003c\/strong\u003e Transcriptomic analysis reveals modulation of neurotransmitter, immune, vascular, and neuroprotection genes.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eWhy Researchers Choose Peptides BioLab\u003c\/h3\u003e\n\u003cp\u003eEvery batch of \u003cstrong\u003eSemax\u003c\/strong\u003e supplied by Peptides BioLab undergoes rigorous HPLC and mass spectrometry analysis, ensuring ≥98% purity verified by an independent Certificate of Analysis (CoA). Our \u003ca href=\"\/products\/semax\"\u003eSemax\u003c\/a\u003e is supplied as a lyophilized powder for maximum stability and shelf life, shipped worldwide from our state-of-the-art facilities in temperature-controlled packaging.\u003c\/p\u003e\n\u003ch3\u003eRelated Research Peptides\u003c\/h3\u003e\n\u003cp\u003eResearchers studying related pathways may also find these compounds relevant: \u003ca href=\"\/products\/selank\"\u003eSelank\u003c\/a\u003e, \u003ca href=\"\/products\/pp-22-28\"\u003ePE-22-28\u003c\/a\u003e, and \u003ca href=\"\/products\/pinealon\"\u003ePinealon\u003c\/a\u003e. Browse our \u003ca href=\"\/collections\/cognitive-function\"\u003eNootropic \u0026amp; Cognitive Research\u003c\/a\u003e collection.\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eFor research purposes only — Not for human consumption. All products are intended solely for in-vitro research and laboratory use.\u003c\/em\u003e\u003c\/p\u003e\n\u003c\/div\u003e","brand":"Peptides BioLab","offers":[{"title":"10","offer_id":60995753312586,"sku":"PBL-SEMAX-10MG","price":29.99,"currency_code":"EUR","in_stock":true},{"title":"30","offer_id":60995753345354,"sku":"PBL-SEMAX-10MG","price":79.99,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0998\/9429\/6906\/files\/peptides-biolab-semax-nootropic-cognitive-peptide-10mg-research-grade.webp?v=1773935027","url":"https:\/\/peptides-biolab.com\/products\/semax","provider":"Peptides BioLab","version":"1.0","type":"link"}