{"product_id":"vip","title":"VIP","description":"\u003cdiv class=\"pb-product-desc\"\u003e\n\u003ch2\u003eVIP — Vasoactive Intestinal Peptide for Neuroimmune and Mucosal Research\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eVIP\u003c\/strong\u003e is a 28-amino acid neuropeptide (Said \u0026amp; Mutt, 1970). Neurotransmitter and immune modulator acting through VPAC1\/VPAC2 receptors across nervous, immune, endocrine, and GI systems. Over 10,000 published articles.\u003c\/p\u003e\n\u003ch3\u003eMechanism of Action\u003c\/h3\u003e\n\u003cp\u003eVIP activates VPAC1\/2 via Gs-cAMP signaling. In neurons: modulates synaptic transmission and circadian rhythm (key SCN synchronizer). In immune cells: generates tolerogenic DCs, promotes Tregs, shifts Th1→Th2 (\u003cem\u003eNat Rev Immunol\u003c\/em\u003e). In gut: regulates ion transport, blood flow, smooth muscle.\u003c\/p\u003e\n\u003ch3\u003eKey Research Areas\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eNeuroimmune Modulation:\u003c\/strong\u003e VIPergic nerves innervate lymphoid organs — studies how neuropeptide signaling regulates immune function.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCircadian Clock Research:\u003c\/strong\u003e Essential for SCN neuronal synchronization. VPAC2 signaling maintains intercellular clock coupling.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eRegulatory T-Cell Biology:\u003c\/strong\u003e Promotes FoxP3+ Treg differentiation — peripheral tolerance and immune homeostasis mechanisms.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGut-Brain Axis:\u003c\/strong\u003e Abundant enteric neuropeptide regulating secretion, motility, barrier function, and mucosal immune responses.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eWhy Researchers Choose Peptides BioLab\u003c\/h3\u003e\n\u003cp\u003eEvery batch of \u003cstrong\u003eVIP\u003c\/strong\u003e supplied by Peptides BioLab undergoes rigorous HPLC and mass spectrometry analysis, ensuring ≥98% purity verified by an independent Certificate of Analysis (CoA). Our \u003ca href=\"\/products\/vip\"\u003eVIP\u003c\/a\u003e is supplied as a lyophilized powder for maximum stability and shelf life, shipped worldwide from our state-of-the-art facilities in temperature-controlled packaging.\u003c\/p\u003e\n\u003ch3\u003eRelated Research Peptides\u003c\/h3\u003e\n\u003cp\u003eResearchers studying related pathways may also find these compounds relevant: \u003ca href=\"\/products\/ara-290\"\u003eARA-290\u003c\/a\u003e, \u003ca href=\"\/products\/thymosin-alpha-1\"\u003eThymosin Alpha-1\u003c\/a\u003e, and \u003ca href=\"\/products\/ll-37\"\u003eLL-37\u003c\/a\u003e. Browse our \u003ca href=\"\/collections\/cognitive-function\"\u003eNeurological Research\u003c\/a\u003e collection.\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eFor research purposes only — Not for human consumption. All products are intended solely for in-vitro research and laboratory use.\u003c\/em\u003e\u003c\/p\u003e\n\u003c\/div\u003e","brand":"Peptides BioLab","offers":[{"title":"Default Title","offer_id":60995752100170,"sku":"PBL-VIP-6G","price":59.99,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0998\/9429\/6906\/files\/peptides-biolab-vip-vasoactive-intestinal-peptide-10mg-research-grade.webp?v=1773933905","url":"https:\/\/peptides-biolab.com\/products\/vip","provider":"Peptides BioLab","version":"1.0","type":"link"}