Selank
Lab-Tested ≥98% Purity · Certificate of Analysis Included · Global Shipping
Selank — Tuftsin-Derived Heptapeptide for Anxiolytic and Cognitive Research
Selank (Thr-Lys-Pro-Arg-Pro-Gly-Pro) is a synthetic tuftsin analog with Pro-Gly-Pro extension for stability. Developed at the Institute of Molecular Genetics, Russian Academy of Sciences. Combined anxiolytic and nootropic properties without sedation or dependence.
Mechanism of Action
Selank allosterically enhances GABA-A receptor sensitivity without direct benzodiazepine-site binding. Increases hippocampal BDNF mRNA. Stabilizes enkephalin levels by inhibiting enkephalinase. Modulates 36 genes related to GABAergic, serotonergic, and dopaminergic neurotransmission in the hippocampus.
Key Research Areas
- GABAergic Modulation: Allosteric GABA-A enhancement providing anxiolytic effects without sedation, tolerance, or withdrawal.
- BDNF and Neuroplasticity: Increased hippocampal BDNF with downstream TrkB-CREB signaling for LTP and memory consolidation.
- Enkephalin Metabolism: Inhibits enkephalin-degrading enzymes for elevated endogenous opioid signaling without mu-agonism.
- Immune-Neuro Crosstalk: Retains tuftsin immunomodulatory properties (phagocytosis, IL-6) for studying nervous-immune bidirectional communication.
Why Researchers Choose Peptides BioLab
Every batch of Selank supplied by Peptides BioLab undergoes rigorous HPLC and mass spectrometry analysis, ensuring ≥98% purity verified by an independent Certificate of Analysis (CoA). Our Selank is supplied as a lyophilized powder for maximum stability and shelf life, shipped worldwide from our state-of-the-art facilities in temperature-controlled packaging.
Related Research Peptides
Researchers studying related pathways may also find these compounds relevant: Semax, PE-22-28, and DSIP. Browse our Nootropic & Cognitive Research collection.
For research purposes only — Not for human consumption. All products are intended solely for in-vitro research and laboratory use.
Every Peptides BioLab product includes a Certificate of Analysis (CoA) with HPLC and MS data confirming ≥98% purity. The CoA is available in the product tabs as the 2nd image, or contact our team to request a copy.
Shipping: We ship worldwide from our state-of-the-art facilities. Orders are processed within 1–2 business days. Express and standard shipping options available at checkout.
Storage: Store lyophilized peptides at -20°C for long-term storage. Once reconstituted, store at 2–8°C and use within 30 days. Keep away from direct sunlight.
