Thymosin Alpha-1
Lab-Tested ≥98% Purity · Certificate of Analysis Included · Global Shipping
Thymosin Alpha-1 — Thymic Peptide for Dendritic Cell Maturation and Immune Research
Thymosin Alpha-1 (Tα1) is a 28-amino acid thymic peptide (Goldstein et al., 1977). Over 4,400 published articles and 80+ clinical trials. Biological response modifier enhancing innate and adaptive immunity through dendritic cell maturation, T-cell differentiation, and TLR signaling. Approved in 35+ countries.
Mechanism of Action
Tα1 activates TLR2 and TLR9, promoting dendritic cell maturation with increased MHC I/II, CD80/CD86, and IL-12 secretion. Drives Th1 differentiation, enhances NK cell cytotoxicity, and stimulates B cell antibody production. Activates p38 MAPK and NF-κB in TLR-dependent manner.
Key Research Areas
- Dendritic Cell Biology: Promotes DC maturation and functional competence — enhanced antigen processing, MHC expression, T-cell priming.
- T-Cell Differentiation: Drives CD4+ Th1 polarization and enhances CD8+ cytotoxic function — T-cell polarization mechanisms.
- TLR Signaling Research: Activates TLR2/TLR9 — studies how thymic peptides modulate pathogen recognition receptors.
- Immune Senescence: Partially reverses age-associated immune decline, restoring T-cell repertoire diversity and NK function.
Why Researchers Choose Peptides BioLab
Every batch of Thymosin Alpha-1 supplied by Peptides BioLab undergoes rigorous HPLC and mass spectrometry analysis, ensuring ≥98% purity verified by an independent Certificate of Analysis (CoA). Our Thymosin Alpha-1 is supplied as a lyophilized powder for maximum stability and shelf life, shipped worldwide from our state-of-the-art facilities in temperature-controlled packaging.
Related Research Peptides
Researchers studying related pathways may also find these compounds relevant: LL-37, KPV, and TB-500. Browse our Immunomodulatory Research collection.
For research purposes only — Not for human consumption. All products are intended solely for in-vitro research and laboratory use.
Every Peptides BioLab product includes a Certificate of Analysis (CoA) with HPLC and MS data confirming ≥98% purity. The CoA is available in the product tabs as the 2nd image, or contact our team to request a copy.
Shipping: We ship worldwide from our state-of-the-art facilities. Orders are processed within 1–2 business days. Express and standard shipping options available at checkout.
Storage: Store lyophilized peptides at -20°C for long-term storage. Once reconstituted, store at 2–8°C and use within 30 days. Keep away from direct sunlight.
